Saturday, December 31, 2011

For Iran, cost of closing strait may outweigh gain (AP)

CAIRO ? With missile batteries, fleets of attack boats and stocks of naval mines, Iran can disrupt traffic through the Strait of Hormuz but probably cannot completely shut down the world's most important oil route, military analysts say. The question for Iran's leadership is whether it is worth the heavy price.

Trying to close the strait would bring down a powerful military response on Iran's head from U.S. forces in the Gulf and turn Tehran's few remaining international allies against it.

That Iran is making such dire threats at all illustrates its alarm over new sanctions planned by the U.S. that will target oil exports ? the most vital source of revenue for its economy. Iran's leaders shrugged off years of past sanctions by the U.S. and United Nations, mocking them as ineffective. But if it cannot sell its oil, its already-suffering economy will be sent into a tailspin.

"It would be very, very difficult for Iran even to impede traffic for a significant period of time," said Jonathan Rue, a senior research analyst at the Washington-based Institute for the Study of War. "They don't have the ability to effectively block the strait."

What the Iranians can do, Rue and other analysts say, is harass traffic through the Gulf ? anything from stopping tankers to outright attacks. The goal would be to panic markets, drive up shipping insurance rates and spark a rise in world oil prices enough to pressure the United States to back down on sanctions.

The strait would seem to be an easy target, a bottleneck only about 30 miles (50 kilometers) across at its narrowest point between Iran and Oman.

Tankers carrying one-sixth of the world's oil supply pass through it, from the fields of petrogiants Iran and its Gulf Arab neighbors, exiting the Persian Gulf into the Arabian Sea and on to market. They move through two two-mile-wide shipping lanes, one entering the Gulf, one exiting.

In recent years, Iran has dramatically ramped up its navy, increasing its arsenal of fast-attack ships, anti-ship missiles and mine-laying vessels. Its elite Revolutionary Guards boasts the most powerful naval forces, with approximately 20,000 men, with at least 10 missile patrol boats boasting C-802 missiles with a range of 70 miles (120 kilometers) and a large number of smaller patrol boats with rocket launchers and heavy machine guns, according to a recent report by Anthony Cordesman at the Center for Strategic and International Studies.

The navy has three submarines and an unknown number of midget subs, capable of firing "smart" torpedoes or laying mines. It also has a large scale capability for laying mines using both small craft and commercial boats, according to the report.

The Revolutionary Guard has also deployed a heavy array of anti-ship Seersucker missiles with a range of up to 60 miles (100 kilometers) along its coast overlooking the strait, on mobile platforms that make them harder to hit.

The Guard's naval forces and the regular navy "have been the most favored service. The Iranian air force and ground forces have not seen the same level of attention in domestic procurement and weapons systems," Rue said. "They realize their navies are the best options for inflicting casualties" on the U.S. or Arab Gulf nations.

Still, those forces would not likely be enough to outright seal the strait, given the presence of the U.S. 5th Fleet based in the Gulf nation of Bahrain. On Wednesday, Pentagon spokesman George Little warned that any "Interference with the transit or passage of vessels through the Strait of Hormuz will not be tolerated."

Laying minefields in the Hormuz waters would in theory be the most effective action, forcing time-consuming clearing by U.S. forces and their allies before tankers could move through.

But particularly strong currents in the strait make such mining difficult. Moreover, the U.S. and its Gulf allies have extensive surveillance in the area, meaning the Iranians would have little time to set an effective minefield, Rue said. The United Arab Emirates and Saudi Arabia have both extensively increased their anti-mining capabilities.

Iran's anti-ship missile batteries on the coast are another major threat. But while the missile platforms are mobile, the radar facilities that enable them to target shipping largely are not, making them vulnerable to U.S. strikes.

"It wouldn't be a cakewalk" for U.S. and other forces to push back an Iranian attempt to close the strait, Rue said. But in the end, "their capabilities are not great and ours overwhelmingly outmatch theirs."

The closest parallel may be the 1980-88 Iran-Iraq war, when each side attacked shipping in the Gulf, trying to cut off the other's vital oil revenues. More than 500 ships were damaged in attacks, and Iranian mining and assaults prompted a U.S. operation escorting Kuwaiti tankers. But while oil shipments from the Gulf slowed, they came nowhere close to stopping.

Alireza Nader, an analyst at the RAND Corp., said Iran could start with lower-level moves short of outright attacks.

"It could harass shipping, stopping and searching ships. We could see those kind of provocative steps," he said.

But turning to military moves raises the danger for Iran of retaliation. And trying to close the strait could be disastrous for Tehran.

"If the benefits are higher than the costs, it could take that action, but it's difficult to see how that could be because of how bad the fallout would be," Nader said. "It's economic self-sabotage."

Hormuz is in the territorial waters of Iran and Oman, but it is considered an international strait where free passage is guaranteed, meaning that under international law, closing it by any nation would be considered an act of war. Russia and China, Iran's main allies that have protected it from stronger U.N. sanctions, would have little choice but to respond. Russia, which now has oil production contracts in Iraq, and China, which relies on the region for its supplies, also have no interest in seeing traffic stop, said Olivier Jakob of the Switzerland-based oil monitor Petromatrix.

Hormuz's closure would also be a heavier blow to Iran than any sanctions hitting the approximately 2.5 billion barrels a day of oil it exports, which provide some 80 percent of its revenue. Not only do all of its oil exports go through the strait, but also most of its imports, including vital gasoline supplies.

"A full shutdown would really be the worse case for Iran. That's their last bullet," Jakob said.

Given that, U.S. officials have expressed doubts Iran would carry out the threat. State Department spokesman Mark Toner called Iran's warnings merely "more rhetoric."

Iran has threatened to close the strait in the past, but in response to a U.S. or Israeli attack on its nuclear facilities. Now it has stepped it up a notch as a possible retaliation to sanctions, reflecting the degree of worry over the planned U.S. sanctions aimed at stopping its nuclear program,

The sanctions would ban transactions with the Iranian Central Bank. Countries and companies around the world use the bank to finance purchases of Iranian oil, meaning they would either have to stop buying it or face action from Washington.

Halting ? or even denting ? oil income would be devastating to an economy that is already struggling amid its international isolation. The value of Iran's riyal is now 15,200 to the dollar, from 10,500 a year ago. Cash withdrawals from banks have been restricted.

Prices of food and grocery items like milk have increased up to 20 percent in recent months. In an attempt to cut its budget, the government recently ended subsidies on fuel and some foods, sending gas prices up sevenfold and quadrupling bread prices. In place of subsidies, the government gives direct payments of $40 a month to poor families to pay for necessities.

The threats also reflect a worry among Iran's leaders that its oil can be replaced on the market by Arab producers, particularly Saudi Arabia, without too great an increase in world prices, said Mustafa Alani, a Geneva-based analyst with the Gulf Research Center. That makes a cutoff a viable option for the U.S., and if that happens "the economy will collapse."

"All the noise about Hormuz is linked to the feeling that it is possible, and they say, 'if we go down, we will take everyone with us.' If Iranian oil stops, then all the oil stops," he said.

But in the end, "I don't think they are willing to do it because the consequences would cost them too much," Alani said. "I don't think they are so stupid."

___

AP correspondents Nasser Karimi in Tehran, Sinan Salaheddin and Rebecca Santana in Baghdad contributed to this report.

Source: http://us.rd.yahoo.com/dailynews/rss/topstories/*http%3A//news.yahoo.com/s/ap/20111230/ap_on_bi_ge/ml_iran_shutting_hormuz

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Actress Patricia Clarkson to lead Carnival parade

By Associated Press ??|??Celeb Stalker??|??December 30, 2011 Patricia Clarkson

Patricia Clarkson (Image via RottenTomatoes.com)

Actress Patricia Clarkson will lead the Carnival parade of the Krewe of Muses in her hometown of New Orleans.

The star of the 2010 thriller ?Shutter Island? and the 2003 drama ?Pieces of April? will step into a whimsical limelight by riding on a red fiber-optic-lit float shaped like a high-heeled shoe.

The Krewe of Muses is an all-women?s organization that parades through New Orleans on Feb. 16.

The krewe traditionally selects an honorary rider who exemplifies a muse from Greek mythology, such as dance, poetry or music. For 2012, the club said it chose Clarkson as its honorary ?EveryMuse? because she embodies the spirit of all muses.

Source: http://www.pbpulse.com/gossip/celeb-stalker/2011/12/30/actress-patricia-clarkson-to-lead-carnival-parade/

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Friday, December 30, 2011

Pre-caffeine: Breaking NORAD, 'Blade Runner' sketches!

via BuzzFeed

By Helen A.S. Popkin

Our pre-caffeine roundup is a collection of the hottest, strangest, and most amusing stories of the morning. Here's everything that you need to know before taking that first sip of coffee today.

Looks like "Dump GoDaddy Day" totally worked. The website hosting company now straight-up denounces SOPA.

Steve Jobs is totally getting a Grammy.

Meanwhile, MySpace is "a cesspool no on wants to visit," says your first friend, Tom.

On Wednesday, Verizon Wireless customers had to deal with yet another data outage. Like previous technical glitches, the outage was resolved within a day's time and Verizon tweeted an obligatory line about things being back to normal.

NORAD says its Santa-tracking operation broke its own records for phone calls, emails and Facebook and Twitter followers on Christmas Eve.

While politicians routinely cite video games as a contributing cause for everything from childhood obesity and lower test scores to youth violence, Sen. Tom Coburn (R-OK) recently labeled a video game museum as something else ? a waste of taxpayer funds.

Speaking of a waste of money, a man in China spent $16,000 for a virtual sword on a game that has not even been released yet.

An Israeli law center is threatening to sue Twitter unless the social network cuts off access to groups, including Hezbollah, that are considered terrorist organizations by the United States.

Meanwhile, Fox Latin America apologized for a poll on whether Jews killed Jesus Christ that one of its staffers put on a Facebook page promoting the National Geographic Channel's Christmas special.

In closing: "Blade Runner" sketch book! "Blade Runner" sketch book!?

? compiled by Helen A.S. Popkin, who invites you to join her on Twitter and/or Facebook.?Also, Google+.??

Source: http://technolog.msnbc.msn.com/_news/2011/12/30/9826117-pre-caffeine-tech-breaking-norad-blade-runner-sketch-book

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Iran threatens to stop Gulf oil if sanctions widened

TEHRAN: Iran threatened on Tuesday to stop the flow of oil through the Strait of Hormuz if foreign sanctions were imposed on its crude exports over its nuclear ambitions, a move that could trigger military conflict with economies dependent on Gulf oil.

Western tensions with Iran have increased since a November 8 report by the U.N. nuclear watchdog saying Tehran appears to have worked on designing an atomic bomb and may still be pursuing research to that end. Iran strongly denies this and says it is developing nuclear energy for peaceful purposes.

Iran has defiantly expanded nuclear activity despite four rounds of U.N. sanctions meted out since 2006 over its refusal to suspend sensitive uranium enrichment and open up to U.N. nuclear inspectors and investigators.

Many diplomats and analysts believe only sanctions targeting Iran's lifeblood oil sector might be painful enough to make it change course, but Russia and China - big trade partners of Tehran - have blocked such a move at the United Nations.

Iran's warning on Tuesday came three weeks after EU foreign ministers decided to tighten sanctions over the U.N. watchdog report and laid out plans for a possible embargo of oil from the world's No. 5 crude exporter.

"If they (the West) impose sanctions on Iran's oil exports, then even one drop of oil cannot flow from the Strait of Hormuz," the official Iranian news agency IRNA quoted Iran's First Vice President Mohammad Reza Rahimi as saying.

The U.S. State Department said it saw "an element of bluster" in the threat but underscored that the United States would support the free flow of oil.

"It's another attempt to distract attention away from the real issue, which is their continued non-compliance with their international nuclear obligations," spokesman Mark Toner said.

Rahimi's remarks coincided with a 10-day Iranian naval exercise in the Strait and nearby waters, a show of military force that began on Saturday.

"Our enemies will give up on their plots against Iran only if we give them a firm and strong lesson," Rahimi said.

JANUARY MEETING

EU ministers said on December 1 that a decision on further sanctions would be taken no later than their January meeting but left open the idea of an embargo on Iranian oil.

Countries in the 27-member European Union take 450,000 barrels per day of Iranian oil, about 18 percent of the Islamic Republic's exports, much of which go to China and India. EU officials declined to comment on Tuesday.

About a third of all sea-borne oil was shipped through the Strait of Hormuz in 2009, according to the U.S. Energy Information Administration, and U.S. warships patrol the area to ensure safe passage.

Most of the crude exported from Saudi Arabia, Iran, the United Arab Emirates, Kuwait and Iraq - together with nearly all the liquefied natural gas from lead exporter Qatar - must slip through the Strait of Hormuz, a 4-mile (6.4 km) wide shipping channel between Oman and Iran.

Iran has also hinted it could hit Israel and U.S. interests in the Gulf in response to any military strike on its nuclear installations - a last resort option hinted at by Washington and the Jewish state.

However, some analysts say Iran would think hard about sealing off the Strait since it could suffer just as much economically as Western crude importers, and could kindle war with militarily superior big powers.

"To me, if Iran did that it would be a suicidal act by the regime. Even its friends would be its enemies," said Phil Flynn, analyst at PFG Best Research in Chicago.

Source: http://www.timesofoman.com/innercat.asp?detail=53190

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Thursday, December 29, 2011

Avastin can stabilize tumors in ovarian cancer, studies find

Avastin can stabilize tumors in women suffering from advanced-stage ovarian cancer, extending the period before the disease worsens by more than 3.5 months, according to the results of two large, international clinical trials conducted by separate research teams.

The findings, published in Thursday's edition of the New England Journal of Medicine, come less than a week after the European Commission approved Avastin for treating women newly diagnosed with advanced ovarian cancer. The drug, known generically as bevacizumab, has not yet been approved by the Food and Drug Administration to treat ovarian cancer in the U.S.

Though Avastin has not been shown to prolong the lives of women with ovarian cancer and does come with significant side effects, it offers some hope for treating what remains the deadliest of gynecologic cancers, researchers said.

Ovarian cancer affects an estimated 200,000 women worldwide and causes 125,000 deaths each year, including more than 15,000 in the U.S. The cancer is particularly difficult to treat because it usually found after it has already spread to other organs. Surgery can remove only some of the tumors, and the two chemotherapy drugs most commonly used aren't very good at killing the cancer cells left behind.

But the study results suggest that treatment for ovarian cancer could improve for the first time in 15 years, said Dr. Robert Burger, a surgical oncologist at Fox Chase Cancer Center and lead author for one of the studies.

"I think we finally have a third component of treatment that works differently and that may greatly complement our therapeutics for ovarian cancers," he said.

Avastin is a biological antibody that interferes with a growth factor that cancer cells need to grow new blood vessels. When used in concert with chemotherapy, the drug helps keep cancers that have metastasized from growing and spreading. The FDA has approved the drug for use in a number of different cancers, including non-small-cell lung, kidney, brain and colon cancer.

Most recently, its use in treating breast cancer has become a source of controversy, as the FDA last month withdrew its approval of Avastin for patients with advanced breast cancer because the modest benefits were not seen as outweighing the drug's side effects. Physicians, however, can still prescribe Avastin off-label.

Burger's team, known as the Gynecologic Oncology Group, looked at what's called progression-free survival ? the length of time before the cancer gets worse ? in 1,873 women with newly diagnosed stage III and stage IV ovarian cancers, which typically have 5-year survival rates ranging from 18% to 45%. The investigators found that patients who received Avastin throughout their chemotherapy treatment experienced 14.1 months of progression-free survival, compared with the 10.3 months for patients who received standard chemotherapy plus a placebo. (Patients who received Avastin only during the initial treatments had 11.2 months of progression-free survival.)

The second study, by the International Collaboration on Ovarian Neoplasms, looked at 1,528 ovarian cancer patients and found a smaller difference in progression-free survival ? 24.1 months for those who took Avastin versus 22.4 months for those who didn't.

But when they focused on the 465 patients with the most advanced cancers, they found a bigger benefit ? 14.5 months with standard therapy alone and 18.1 months with Avastin added. They also found that overall survival for these patients was better with Avastin, at 28.8 versus 36.6 months.

On the whole, however, the researchers said they would not able to say much about overall survival rates until the patients had been tracked for a few more years.

The studies documented some notable side effects from the drug, including an increased risk of hypertension and gastrointestinal wall disruption, when a hole develops in the gastrointestinal tract. But these problems did not affect patients' quality of life, both studies found.

Avastin does not come cheap. The drug, made by Genentech Inc., can cost about $50,000 to $100,000 a year, which may be a lot to pay for just a few months more of remission, said Dr. Joanne Mortimer, director of the Women's Cancers Program at the City of Hope Comprehensive Cancer Center in Duarte. Many insurance companies cover at least some of that cost.

"Is it worth it?" said Mortimer, who served on two of three FDA advisory panels that debated the use of Avastin for breast cancer. "These are positive studies, but are they meaningful differences?"

Though the answer for breast cancer was no, the answer for ovarian cancer may be different, she said. Drugs for breast cancer are held to a higher standard because much more is known about how to treat the disease. The bar is lower for ovarian cancer because the treatment options aren't as good, Mortimer said.

Dr. Timothy Perren, a medical oncologist at Spire Leeds Hospital in Yorkshire, England, who led the second study, said the trials were promising steps that would "cement the place of Avastin in treating ovarian cancer." But researchers from both groups noted that more work needed to be done to figure out which patients would benefit the most from the drug and the best way to administer it.

The studies were funded by the National Institutes of Health, the National Institute for Health Research in Britain, Genentech and its parent company, Roche.

amina.khan@latimes.com

Source: http://feedproxy.google.com/~r/latimes/news/nationworld/nation/~3/z4bMX1jbu4Y/la-he-avastin-ovarian-cancer-20111229,0,3960902.story

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Wednesday, December 28, 2011

Funeral pending for Texas woman, children killed in Veracruz

Read?more: Local, State, Crime, Christina Hartsell, Maria Hartsell, Karla Hartsell, Margaret Schneider, Passenger Bus Attack, Drug War, Deadly Attack, Drug Cartels, Gunmen, El Higo, Veracruz, Cleburne, Texas Action 4 News Rio Grande Valley, Mexico

Funeral arrangements are being made for a Cleburne, Texas mother and two teenage sisters killed by gunmen attacking a passenger bus in Veracruz.

Maria Hartsell was on a bus heading to visit her mother in Veracruz last Thursday when gunmen stormed the bus in a robbery spree.

The gunmen killed seven people aboard three passenger buses.

Just days before leaving to visit family in Mexico, 13-year-old Christina Hartsell wrote her father - urging him, 'don't worry.'

The teen took pictures of her journey south but travelling overnight on Mexico's highways proved more dangerous than she imagined.

?It's tragic what happened,? Christina?s grandmother Margaret Schneider told KTVT-TV. ?It was just a tragedy, totally unnecessary.?

Schneider learned Thursday about that happened.

The gunmen killed Christina, her mother Maria and Christina's half-sister Karla.

?I'm not her biological grandma, Karla's, but I loved her like my own,? Schneider told the Dallas-based TV station. ?She always came up and gave me a hug and said, I love you grandmother.?

The suspected drug cartel attack targeting innocent civilians is leaving many puzzled.

?I just don't understand why they would kill those girls,? Schneider said. ?I just don't understand.?

Two other siblings survived the attack: 15-year-old Angie, who suffers from down syndrome and 10-year-old Micheal.

?His mother getting shot, his sisters getting shot - he witnessed it all,? Schneider said.

The grieving grandmother said her daughter-in-law Maria was anxious to see her own ailing mother and ignored warnings not to travel to Mexico.

?All the family advised her not to go, but she still went,? Schneider said.?

Source: http://www.valleycentral.com/news/story.aspx?id=701303

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Source: community.netscape.com --- Monday, December 26, 2011
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Source: http://community.netscape.com/dir-app/acx/ACDispatch.aspx?action=message&webtag=ws-winsupport&msg=196985

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Tuesday, December 27, 2011

Top Five Music Videos Of 2011

So 2011 has been a great musical year. Every year, I like to round up my favorite music videos for readers to enjoy. So come and check them out and share what your favorites are! So this year we have the same big names: Rihanna, Britney Spears, Katy Perry, The Black Eyed Peas, and Lady Gaga. these hipsters know how to rock out and make amazing videos for their fans. That is why they are definitely in my top five favorites! Here is my list. No, you don’t have to agree, that’s part of the fun. Join in the comments or tweet @rightcelebrity to share your list! Rihanna: “We Found Love” This is my favorite video of 2011 because I related most to it. Rihanna made this controversial video while on her Loud Tour in Europe. She gained attention when the owner of the rural farm they shot on asked her to stop cause of her racy outfit. It wasn’t that bad! I love this video and song because it has an old school feel to it – the sound is like old beats I would have listened to back in my troubled teen years while having some of the [...]

Source: http://feedproxy.google.com/~r/RightCelebrity/~3/aS26u1h494w/

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journeydan: Omg I only got an iPhone and iPad but what I really wanted was a pony. Screw you, mom & dad.

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Omg I only got an iPhone and iPad but what I really wanted was a pony. Screw you, mom & dad. journeydan

Daniel Bader

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Sunday, December 25, 2011

the_str: Video - Forehead: The Pope, Prophet and Buddha of the GOP Wants to Sabotage Economy - Rush Limbaugh http://t.co/VFqLORDM

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Video - Forehead: The Pope, Prophet and Buddha of the GOP Wants to Sabotage Economy - Rush Limbaugh rushlimbaugh.com/videos#uri=cha? the_str

Steven Bravo

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dpbkmb: RT @ifeelgod: Church Technology Poll: Do You Speak or Preach From A Tablet Or E-reader? http://t.co/9dB1QqSV

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RT @ifeelgod: Church Technology Poll: Do You Speak or Preach From A Tablet Or E-reader? goo.gl/fb/Pknmh dpbkmb

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Saturday, December 24, 2011

Boehner's Words for the Ages (talking-points-memo)

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FBI: Geezer Bandit may be too spry to be a senior (Providence Journal)

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amcgowanca: Time to go get the last gift I need to buy for this Christmas, then back home to work on a list of to-dos :) #lovingit

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Time to go get the last gift I need to buy for this Christmas, then back home to work on a list of to-dos :) #lovingit amcgowanca

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Campbell (SID): CBSSports.com: Griffin could be first NBA player from Campbell

December 22, 2011

WILMINGTON, N.C. ? Campbell University has never had a player reach the NBA. Considering the Fighting Camels have only reached one NCAA tournament, that's probably not a surprise.

Could Campbell break through and produce an NBA prospect this season? The school has its best chance in years with senior forward Eric Griffin.

Click here for the full story from CBSSports.com

Editor's Note:? Former Campbell junior college standout George Lehmann went on to play in the NBA and ABA.

Source: http://www.bbstate.com/news/442473

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Friday, December 23, 2011

Oracle sinks Nasdaq; Dow, S&P hold firm (Reuters)

NEW YORK (Reuters) ? Technology shares slumped on Wednesday and pushed the Nasdaq down 1 percent after Oracle reported results that cast doubts on the sector's health, even as broader markets closed mostly flat in a thinly traded day.

Outside the Nasdaq, the market recovered from early losses as some recent fears over Europe faded. Traders tried to build momentum for a year-end rally and possibly erase the S&P 500's 1.1 percent losses so far in 2011.

After Tuesday's close, Oracle Corp (ORCL.O) reported earnings and sales that missed expectations for the first time in a decade. The software giant joins a growing list of companies, including some of technology's biggest and oldest names, whose results and outlooks have raised alarm bells about business conditions.

The stock plunged 12 percent to $25.77 on heavy volume and was the top decliner in the Nasdaq 100 (.NDX). Shares of other tech companies also fell. IBM (IBM.N) was the biggest drag on the Dow, down 3.1 percent at $181.47. Cisco Systems Inc (CSCO.O) lost 2.6 percent to $17.92 at the close. The Philadelphia semiconductor index (.SOX) fell 1.2 percent.

"Oracle is a tech story, but there's concern it could be a broader economic story," said Brad Sorensen, director of market and sector analysis at Charles Schwab in Denver. "We're not ready to go that far yet, but it does show that businesses are unsure about the economic situation, especially with all the uncertainty about Europe."

Despite that, Sorensen said the light volume ahead of the Christmas and New Year's holidays would exacerbate market volatility, making the moves "a little more dramatic than normal."

The Dow Jones industrial average (.DJI) rose 4.16 points, or 0.03 percent, to 12,107.74. The Standard & Poor's 500 Index (.SPX) gained 2.42 points, or 0.19 percent, to 1,243.72. The Nasdaq Composite Index (.IXIC) slid 25.76 points, or 0.99 percent, to 2,577.97.

For the year, the Dow is up 4.6 percent while the Nasdaq is down 2.8 percent.

In Europe, investors worried that cut-rate loans from the European Central Bank's recent funding operation would not be used to buy Italian and Spanish debt, which would help lower elevated yields and reduce the pressure on refinancing for the debt-stricken countries.

European banks took nearly 490 billion euros in three-year cut-price loans from the European Central Bank on Wednesday. While a widening of the yield spread between German and Italian debt initially suggested that money was not flowing where it is most needed, those concerns faded toward the end of the day.

"As investors digest what the ECB is doing, there's some recognition of the fact that European banks are better off having more money on their balance sheets even if it isn't being lent out," said Mike Shea, a managing partner and trader at Direct Access Partners LLC in New York.

An Italian banking group said banks would not increase their exposure to sovereign debt even after the ECB offering because European Bank Authority rules discourage it.

Ryan Larson, head of equity trading at RBC Global Asset Management in Chicago, said unconfirmed talk was circulating in the market that banks would use ECB loans to buy German bonds and not to support the debt of Spain and Italy.

"That kind of spooked the market," he said. "While it is a positive development in terms of the lending facility, there are still a lot of problems out there."

He said he was not able to confirm any of the market speculation.

Tuesday's rally had lifted the S&P 500 above its 50-day moving average. Many investors and traders are looking for a seasonal "Santa rally" through the end of the year and are keen to jump on any signs of momentum.

U.S.-listed shares of Research in Motion Ltd (RIMM.O)(RIM.TO) jumped 10.1 percent to $13.78 and ranked as the Nasdaq 100's top gainer after Reuters reported that Amazon (AMZN.O) and other potential bidders had been looking at making an offer for the BlackBerry maker, although interest had cooled somewhat.

The latest economic data showed sales of previously owned U.S. homes surged in November, but revisions to data for the last four years gave proof that the housing market's recession was deeper than previously thought.

Contract electronics manufacturer Jabil Circuit Inc (JBL.N) posted first-quarter revenue below estimates and said it sees lower revenue in the second quarter. Shares fell 2.8 percent to $19.40.

Volume was light, with about 6.52 billion shares traded on the New York Stock Exchange, the American Stock Exchange and Nasdaq, below last year's daily average of 8.47 billion.

About 59 percent of companies traded on the New York Stock Exchange closed in positive territory while about 48 percent of the Nasdaq ended lower.

(Reporting by Ryan Vlastelica; Editing by Jan Paschal)

Source: http://us.rd.yahoo.com/dailynews/rss/business/*http%3A//news.yahoo.com/s/nm/20111221/bs_nm/us_markets_stocks

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'X Factor' Behind The Scenes: Prepping Finale Surprises

Top three contestants Chris Rene, Melanie Amaro and Josh Krajcik rehearse duets, holiday tunes and final performances.
By Jim Cantiello


Chris Rene, Melanie Amaro and Josh Krajcik
Photo: Ray Mickshaw / FOX

It's finale week at "The X Factor," and for the first time all season, rehearsals went late. Like, really late. Like, "I guess I'm not watching 'Conan' tonight" late.

But nobody's complaining. Each contestant is performing three songs Wednesday night (December 21), and the final three singers are eager to get as much practice as possible. Between the competition and the massive surprise-filled two-night finale, you will not find Chris Rene, Melanie Amaro or Josh Krajcik without headphones on, lyric sheets out, stress lines on their foreheads.

Part of the added pressure is that the producers are making the top three prep a "top two" duet. But because the results are unknown, every potential top-two configuration is being rehearsed. By the end of Monday's epic rehearsals, everyone was sick of the duet song.

Despite the high stakes, a moment of levity will enter Stage 36 every now and then. On Tuesday, the background singers presented Chris Rene with a holiday-themed rewrite of his original "Young Homie." (Think "Young homie, what you eatin' on?" and swap out lyrics about sobriety with verses about greens and cornbread.)

Speaking of the holidays, the top three will be getting viewers in the mood to celebrate with some familiar tunes, although one contestant who shall remain nameless couldn't quite grasp the lyrics or the melody of a song everyone knows, which drove their mentor to bark, "That's not a $5 million rehearsal." Bah humbug!

Judge Simon Cowell told the press Monday that he switched one of Amaro's songs because it was "too British." I can't reveal what the song was, but I can say it would have been a very unexpected choice for the resident diva. (On the original recording, there's an extended flute solo. There, I've said too much.) Cowell ultimately decided it was too risky. Will his picks get criticized for being "too safe"?

Spotted: Krajcik in a crew headset carrying equipment backstage. What a hands-on dude! (Turns out, he was just shooting a silly video for the wrap party.)

Behind the scenes, the crew is buzzing about how unpredictable Thursday night's results will be. From the stage hands to the talent handlers, everyone shrugs when asked, "Who do you think will win?" Unlike other talent shows they've worked on, everyone agrees this might be the first finale in a long while where the winner is not clearly telegraphed.

One thing is official: The top three are being treated like celebrities. How do I know? They finally have their own stand-ins for results rehearsals! All season long, only the judges have had stand-ins, but this week, the crew also worked with faux-Melanie, faux-Josh and faux-Chris. Personally, I wish the stand-ins resembled the contestants more, but I suppose it's also fun to imagine Krajcik as a 6'4" dude with a buzzed head.

And now, I'll end my final backstage report with a tidbit from the files of my favorite: craft service! As a thank you to the crew, "The X Factor" producers treated the staff to a massive steak lunch, big enough for a Flintstones family reunion. It gave the final week in "X"-land a very "end of summer camp" vibe. Lots of hugs, lots of email addresses being exchanged, and then there was Cowell himself, who told me off-camera that this is the first series he's worked on in a while where he hasn't burned out by the finale. "I'm a little sad the season is ending," he said.

You and me both, Simon.

Off you go, "The X Factor." Until next fall ...

Who should win "X Factor"? Sound off below!

Source: http://www.mtv.com/news/articles/1676390/x-factor-finale-behind-the-scenes.jhtml

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New take on impacts of low dose radiation

ScienceDaily (Dec. 20, 2011) ? Researchers with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab), through a combination of time-lapse live imaging and mathematical modeling of a special line of human breast cells, have found evidence to suggest that for low dose levels of ionizing radiation, cancer risks may not be directly proportional to dose. This contradicts the standard model for predicting biological damage from ionizing radiation -- the linear-no-threshold hypothesis or LNT -- which holds that risk is directly proportional to dose at all levels of irradiation.

"Our data show that at lower doses of ionizing radiation, DNA repair mechanisms work much better than at higher doses," says Mina Bissell, a breast cancer researcher with Berkeley Lab's Life Sciences Division. "This non-linear DNA damage response casts doubt on the general assumption that any amount of ionizing radiation is harmful and additive."

Bissell was part of a study led by Sylvain Costes, a biophysicist also with Berkeley Lab's Life Sciences Division, in which DNA damage response to low dose radiation was characterized simultaneously across both time and dose levels. This was done by measuring the number of RIF, for "radiation induced foci," which are aggregations of proteins that repair double strand breaks, meaning the DNA double helix is completely severed.

Berkeley Lab biophysicist Sylvain Costes is generating 3D time lapse of DNA repair centers in human cells to understand better how cancer may arise from DNA damage. (Photo by Roy Kaltschmidt, Berkeley Lab)

"We hypothesize that contrary to what has long been thought, double strand breaks are not static entities but will rapidly cluster into preferred regions of the nucleus we call DNA repair centers as radiation exposure increases," says Costes. "As a result of this clustering, a single RIF may reflect a center where multiple double strand breaks are rejoined. Such multiple repair activity increases the risks of broken DNA strands being incorrectly rejoined and that can lead to cancer."

Costes and Bissell have published the results of their study in the Proceedings of the National Academy of Sciences. Also co-authoring the paper were Teresa Neumaier, Joel Swenson, Christopher Pham, Aris Polyzos, Alvin Lo, PoAn Yang, Jane Dyball, Aroumougame Asaithamby, David Chen and Stefan Thalhammer.

The authors believe their study to be the first to report the clustering of DNA double strand breaks and the formation of DNA repair centers in human cells. The movement of the double strand breaks across relatively large distances of up to two microns led to more intensely active but fewer RIF. For example, 15 RIF per gray (Gy) were observed after exposure to two Gy of radiation, compared to approximately 64 RIF/Gy after exposure to 0.1Gy. One Gy equals one joule of ionizing radiation energy absorbed per kilogram of human tissue. A typical mammogram exposes a patient to about 0.01Gy.

Corresponding author Costes says the DNA repair centers may be a logical product of evolution.

"Humans evolved in an environment with very low levels of ionizing radiation, which makes it unlikely that a cell would suffer more than one double strand break at any given time," he says. "A DNA repair center would seem to be an optimal way to deal with such sparse damage. It is like taking a broken car to a garage where all the equipment for repairs is available rather than to a random location with limited resources."

However, when cells are exposed to ionizing radiation doses large enough to cause multiple double strand breaks at once, DNA repair centers become overwhelmed and the number of incorrect rejoinings of double strand breaks increases.

"It is the same as when dozens of broken cars are brought to the same garage at once, the quality of repair is likely to suffer," Costes says.

The link between exposure to ionizing radiation and DNA damage that can give rise to cancerous cells is well-established. However, the standards for cancer risks have been based on data collected from survivors of the atomic bomb blasts in Japan during World War II. The LNT model was developed to extrapolate low dose cancer risk from high dose exposure because changes in cancer incidence following low dose irradiation are too small to be measurable. Extrapolation was done on a linear scale in accordance with certain assumptions and the laws of physics.

"Assuming that the human genome is a target of constant size, physics predicts DNA damage response will be proportional to dose leading to a linear scale," Costes explains. "Epidemiological data from the survivors of the atomic bombs was found to be in agreement with this hypothesis and showed that cancer incidence increases with an increase in ionizing radiation dose above 0.1 Gy. Below such dose, the picture is not clear."

Previous studies failed to detect the clustering of double break strands and the formation of DNA repair centers because they were based on single-time or single-dose measurements of RIF at a discrete time after the initial exposure to ionizing radiation. This yields a net number of RIF that does not account for RIF that have not yet appeared or RIF that have already made repairs and disappeared. The time-lapse imaging used by Costes, Bissell and their co-authors showed that RIF formation continues to occur well beyond the initial radiation exposure and after earlier repair issues have been resolved. Time-lapse imaging also indicates that double strand break clustering takes place before any RIF are formed.

"We hypothesize that double strand break clustering occurs rapidly after exposure to ionizing radiation and that RIF formation reflects the repair machinery put in place around a single cluster of double strand breaks," Costes says. "Our results provide a more accurate model of RIF dose response, and underscore fundamental concerns about static image data analysis in the dynamic environment of the living cell."

Previous studies also mostly involved fibroblast cells whereas Costes, Bissell and their colleagues examined epithelial cells, specifically an immortalized human breast cell line known as MCF10A, which has a much higher background of RIF than fibroblasts, even without ionizing irradiation. To compensate for this higher background, Costes developed a mathematical method that enables background to be corrected for on a per- nucleus basis in unirradiated cells. Still the use of a special line of immortalized breast cells is an issue that Costes and his colleagues plan to address.

"We are now looking at primary breast epithelial cells that have been removed from healthy donors to determine if our results are repeated beyond just a single cell line and under more realistic physiological conditions," Costes says. "We'd also like to know if our findings hold true for fibroblasts as well as epithelial cells. Also, we'd like to know if double strand break clustering is the result of a random coalescence or if there is an active transport mechanism that moves these double strand breaks towards pre-existing DNA repair centers."

Working in collaboration with Rafael Gomez-Sjoberg of Berkeley Lab's Engineering Division, Costes and his group are also developing a special microfluidics lab-on-a-chip device that is integrated into an X-ray microbeam. The goal is to provide a means by which cells can be kept in a controlled microenvironment while being irradiated with multiple doses. This microfluidic array will be used to characterize DNA damage response in breast and blood cells collected from human donors.

"By characterizing DNA damage response in cells from many different human donors," Costes says, "we should be able to determine the variation across humans and gain a better understanding of how sensitivity to DNA damage from ionizing radiation might vary from individual to individual."

This research was supported by the DOE Office of Science.

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The above story is reprinted from materials provided by DOE/Lawrence Berkeley National Laboratory.

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Journal Reference:

  1. T. Neumaier, J. Swenson, C. Pham, A. Polyzos, A. T. Lo, P. Yang, J. Dyball, A. Asaithamby, D. J. Chen, M. J. Bissell, S. Thalhammer, S. V. Costes. Evidence for formation of DNA repair centers and dose-response nonlinearity in human cells. Proceedings of the National Academy of Sciences, 2011; DOI: 10.1073/pnas.1117849108

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/uRe5iJfbk0M/111220133911.htm

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Pa. court tosses sex-for-tickets conviction (AP)

PHILADELPHIA ? An appeals court has overturned the attempted prostitution conviction of a Philadelphia woman who was accused of offering sexual favors for World Series tickets.

Authorities had alleged that Susan Finkelstein posted a racy online ad, then met with an undercover Bensalem police officer in October 2009 and offered to perform sexual acts in exchange for tickets to see the Philadelphia Phillies and New York Yankees.

Finkelstein acknowledged placing a "goofy" ad on Craigslist and hoping to use her "feminine wiles" to get tickets, but denied offering favors and said she wasn't a prostitute.

At trial last year, Finkelstein was acquitted of prostitution but convicted of attempted prostitution.

The state Superior Court ruled Tuesday that since Finkelstein was cleared of the more serious prostitution count, she could not be convicted of attempt because the proof required to sustain both charges was the same. Also, the court noted, Finkelstein was not engaged in "sexual activity as a business" and said the crime of prostitution was not intended to "criminalize private illicit sexual relations."

Finkelstein's attorney, William Brennan, said his client was elated by the decision.

"This woman should never have been charged in the first place," he said.

Stephen Harris, chief of appeals for the Bucks County district attorney, said prosecutors disagree with the court's reasoning but that no decision has been made on whether to appeal.

"Our view is that if you're selling sex for something of value, and certainly a World Series ticket is something of value, that is a business transaction," he said.

Source: http://us.rd.yahoo.com/dailynews/rss/sports/*http%3A//news.yahoo.com/s/ap/20111220/ap_on_sp_ot/us_sex_for_tickets

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Thursday, December 22, 2011

Do our medicines boost pathogens?

ScienceDaily (Dec. 21, 2011) ? Scientists of the Institute of Tropical Medicine (ITG) discovered a parasite that not only had developed resistance against a common medicine, but at the same time had become better in withstanding the human immune system. With some exaggeration: medical practice helped in developing a superbug. For it appears the battle against the drug also armed the bug better against its host.

"To our knowledge it is the first time such a doubly armed organism appears in nature," says researcher Manu Vanaerschot, who obtained a PhD for his detective work at ITG and Antwerp University. "It certainly makes you think."

Vanaerschot studies the Leishmania parasite, a unicellular organism that has amazed scientists before. Leishmania is an expert in adaptation to different environments, and the only known organism in nature disregarding a basic rule of biology: that chromosomes ought to come in pairs. (The latter was also discovered by ITG-scientists recently.) The parasite causes leishmaniasis, one of the most important parasitic diseases after malaria. It hits some two million people, in 88 countries -- including European ones -- and yearly kills fifty thousand of them. The parasite is transmitted by the bite of a sand fly. The combined resistance against a medicine and the human immune system emerged in Leishmania donovani, the species causing the deadly form of the disease.

On the Indian subcontinent, where most cases occur, the disease was treated for decades with antimony compounds. As was to be expected, the parasite adapted to the constant drug pressure, and evolved into a form resisting the antimonials. In 2006 the treatment was switched to another medicine, because two patients out of three did not respond to the treatment. The antimonials closely work together with the human immune system to kill the parasite. This probably has given Leishmania donovani the opportunity to arm itself against both. It not only became resistant against the drug, but also resists better to the macrophages of its host. Macrophages are important cells of our immune system.

There is no absolute proof yet (among other things, because one obviously cannot experiment on humans) but everything suggests that resistant Leishmania not only survive better in humans -- have a higher "fitness" -- but also are better at making people ill -- have a higher "virulence" -- than their non-resistant counterparts.

Superbug?

It is the first time that science finds an organism that always benefits from its resistance. Normally resistance is only useful when a pathogen is bombarded by drugs; the rest of the time it is detrimental to the organism.

Resistant organisms are a real problem to medicine. More and more pathogens become resistant to our drugs and antibiotics -- to a large extend because you and I use them too lavishly and improperly. For several microbes, the arsenal of available drugs and antibiotics has so diminished that people may die again from pneumonia, or even from ulcerating wounds. Luckily for us, resistance helps pathogens only in a drug-filled environment. In the open field their resistance is a disadvantage to them, because they have to invest energy and resources into a property with no use there. Just like a suit of armour is quite useful on the battle field, but a real nuisance the rest of the time.

So the propagation of resistant organisms is substantially slowed down because they are at a disadvantage outside of sick rooms. But this rule, too, is violated by Leishmania: even in absence of the drug, the resistant parasite survives better, instead of worse, and it is more virulent than a non-resistant parasite.

Did our medicines create a superbug? A legitimate question, and the phenomenon has to be investigated, but this sole case doesn't imply we better stop developing new medicines (as a matter of fact, the antimony-resistant Leishmania are still susceptible to a more recent drug, miltefosine). On the contrary, we should develop more new drugs, to give new answers to the adaptive strategies of pathogens, and we should protect those drugs, for instance by using them in combination therapies. In this never-ending arms race we should use our drugs wisely, to minimise the chances for pathogens to develop resistance.

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Source: http://www.sciencedaily.com/releases/2011/12/111221091727.htm

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Monday, December 19, 2011

Genome tree of life is largest yet for seed plants

Friday, December 16, 2011

Scientists at the American Museum of Natural History, Cold Spring Harbor Laboratory, The New York Botanical Garden, and New York University have created the largest genome-based tree of life for seed plants to date. Their findings, published today in the journal PLoS Genetics, plot the evolutionary relationships of 150 different species of plants based on advanced genome-wide analysis of gene structure and function. This new approach, called "functional phylogenomics," allows scientists to reconstruct the pattern of events that led to the vast number of plant species and could help identify genes used to improve seed quality for agriculture.

"Ever since Darwin first described the 'abominable mystery' behind the rapid explosion of flowering plants in the fossil record, evolutionary biologists have been trying to understand the genetic and genomic basis of the astounding diversity of plant species," said Rob DeSalle, a corresponding author on the paper and a curator in the Museum's Division of Invertebrate Zoology who conducts research at the Sackler Institute for Comparative Genomics. "Having the architecture of this plant tree of life allows us to start to decipher some of the interesting aspects of evolutionary innovations that have occurred in this group."

The research, performed by members of the New York Plant Genomics Consortium, was funded by the National Science Foundation (NSF) Plant Genome Program to identify the genes that caused the evolution of seeds, a trait of important economic interest. The group selected 150 representative species from all of the major seed plant groups to include in the study. The species span from the flowering variety?peanuts and dandelions, for example?to non-flowering cone plants like spruce and pine. The sequences of the plants' genomes?all of the biological information needed to build and maintain an organism, encoded in DNA?were either culled from pre-existing databases or generated, in the field and at The New York Botanical Garden in the Bronx, from live specimens.

With new algorithms developed at the Museum and NYU and the processing power of supercomputers at Cold Spring Harbor Laboratory and overseas, the sequences?nearly 23,000 sets of genes (specific sections of DNA that code for certain proteins)?were grouped, ordered, and organized in a tree according to their evolutionary relationships. Algorithms that determine similarities of biological processes were used to identify the genes underlying species diversity.

"Previously, phylogenetic trees were constructed from standard sets of genes and were used to identify the relationships of species," said Gloria Coruzzi, a professor in New York University's Center for Genomics and Systems Biology and the principal investigator of the NSF grant. "In our novel approach, we create the phylogeny based on all the genes in a genome, and then use the phylogeny to identify which genes provide positive support for the divergence of species."

The results support major hypotheses about evolutionary relationships in seed plants. The most interesting finding is that gnetophytes, a group that consists mostly of shrubs and woody vines, are the most primitive living non-flowering seed plants?present since the late Mesozoic era, the "age of dinosaurs." They are situated at the base of the evolutionary tree of seed plants.

"This study resolves the long-standing problem of producing an unequivocal evolutionary tree of the seed plants," said Dennis Stevenson, vice president for laboratory research at The New York Botanical Garden. "We can then use this information to determine when and where important adaptations occur and how they relate to plant diversification. We also can examine the evolution of such features as drought tolerance, disease resistance, or crop yields that sustain human life through improved agriculture."

In addition, the researchers were able to make predictions about genes that caused the evolution of important plant characteristics. One such evolutionary signal is RNA interference, a process that cells use to turn down or silence the activity of specific genes. Based on their new phylogenomic maps, the researchers believe that RNA interference played a large role in the separation of monocots?plants that have a single seed leaf, including orchids, rice, and sugar cane?from other flowering plants. Even more surprising, RNA interference also played a major role in the emergence of flowering plants themselves.

"Genes required for the production of small RNA in seeds were at the very top of the list of genes responsible for the evolution of flowering plants from cone plants," said Rob Martienssen, a professor at Cold Spring Harbor Laboratory. "In collaboration with colleagues from LANGEBIO [Laboratorio Nacional de Genomica para la Biodiversidad] in Mexico last year, we found that these same genes control maternal reproduction, providing remarkable insight into the evolution of reproductive strategy in flowering plants."

The data and software resources generated by the researchers are publicly available and will allow other comparative genomic researchers to exploit plant diversity to identify genes associated with a trait of interest or agronomic value. These studies could have implications for improving the quality of seeds and, in turn, agricultural products ranging from food to clothing.

In addition, the phylogenomic approach used in this study could be applied to other groups of organisms to further explore how species originated, expanded, and diversified.

"The collaboration among the institutions involved here is a great example of how modern science works," said Sergios-Orestis Kolokotronis, a term assistant professor at Columbia University's Barnard College and a research associate at the Museum's Sackler Institute. "Each of the four institutions involved has its own strengths and these strengths were nicely interwoven to produce a novel vision of plant evolution."

###

American Museum of Natural History: http://www.amnh.org

Thanks to American Museum of Natural History for this article.

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Source: http://www.labspaces.net/116103/Genome_tree_of_life_is_largest_yet_for_seed_plants

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Film details Jerry Lewis' 'Method to the Madness' (AP)

LOS ANGELES ? Gregg Barson is a documentarian, not a comedian. But when Jerry Lewis let him know that more than a dozen people were waiting in line to tell his story, Barson offered a persuasive punch line.

"Yeah, but they're not me," was Barson's comeback, followed by a momentary quiver of fear that he'd gone too far with the veteran star.

"He said, `I like that. You know why? Because you remind me of me,'" Barson recalled. That chutzpah-fueled exchange led to "Method to the Madness of Jerry Lewis," debuting 8 p.m. EST Saturday on Encore. Other airings include 11:30 a.m. EST Sunday and 8 p.m. EST Tuesday.

The film focuses on what makes the 85-year-old ? and still working ? Lewis tick as a performer and filmmaker. Those looking for dish on his family life or breakup with stage and screen partner Dean Martin or abrupt departure from the Muscular Dystrophy Association telethon he'd nurtured for nearly five decades won't find it here.

Barson, who describes himself as being "in heaven" whenever he caught a Lewis film on TV as a youngster, said his intent was to focus on Lewis' career from vaudeville on and his contributions to comedy and movies.

Younger people without exposure to Lewis' work likely consider him as "that telethon guy. Hopefully, the film will open their eyes as opposed to thinking he did one thing one day a year," Barson said.

During more than three years of filming, Barson had near-complete access as he followed Lewis from his yacht in San Diego to his home in Las Vegas to concert dates and to the Cannes Film Festival in France, the country that idolizes Lewis as a cinematic genius.

He was good company, Barson said. "He's always up, funny and playful. ... The sparkle, he didn't put in on for the camera. He's being real."

"Method to the Madness," which opens with Jerry Seinfeld, Eddie Murphy and other comedians anointing Lewis as comedy royalty, is an unabashed valentine. It is also a reminder that Lewis inspired rock-star levels of fan devotion, and of how impressively "The Bellboy" (1960) and many other films starring and written and directed by Lewis ruled the box office.

Barson, who made the well-received Phyllis Diller documentary "Goodnight, We Love You," sees parallels between Diller and Lewis, including their work ethic.

"She was 84 when she retired, and he's 85 and still working. They never rest on their laurels," Barson said. "They still care. They're not phoning it in."

And that, he said, is part of Lewis' method: Every aspect of his performance is planned.

"As Eddie Murphy says (in the film), slapstick looks simple but the reason it's been around so long is how well thought out it is," Barson said.

Lewis is pleased with the film. And his health is good, according to the filmmaker, who spills one appropriately quirky personal secret on his subject: "He drinks a lot of orange soda. Maybe that's the fountain of youth."

Source: http://us.rd.yahoo.com/dailynews/rss/tv/*http%3A//news.yahoo.com/s/ap/20111217/ap_en_tv/us_tv_jerry_lewis

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