Saturday, December 29, 2012

Unilever to phase out 'microplastics' by 2015

AMSTERDAM (AP) ? Unilever, the maker of Vaseline, Axe deodorants and Dove soaps, among other cosmetic and hygiene products, says it will phase out the use of microplastics by 2015.

Many soaps, skin scrubs and shower gels contain microplastics, which are tiny polyethelene beads. Scientists and environmental groups are concerned that they contribute to polluting oceans.

The company said Thursday that it has "decided to phase out the use of plastic micro beads as a 'scrub' material in all of our personal care products" by 2015.

Unilever is one of the world's largest consumer product companies, competing with Nestle SA and Procter & Gamble Co.

Source: http://news.yahoo.com/unilever-phase-microplastics-2015-225356615--finance.html

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Friday, December 28, 2012

Realty Times - Housing That Caters To Baby Boomers: Which ...

Perhaps it's no surprise that housing design trends are catering to baby boomers. This is, after all, a huge demographic. Nationwide areas, such as California, are favoring practical designs that aim to serve the baby boomer population.

The National Association of Home Builders says this generation is the largest (76 million) and is looking to postpone or even skip the retirement home and instead find homes that meet their needs continuously as they age. This demographic (those born between the years 1946 and 1964) is also healthier and more active than previous generations. That makes this group want housing that's technologically sophisticated and also offers plenty of other options.

What are the top priorities? Smaller and more efficiently designed homes that are closer to work and entertainment centers. A term we're hearing a lot, "multiple generational housing", is also top of mind when designing for baby boomers. These are homes where many generations of the same family will live together yet have private areas as well as combined living space under one roof. This type of housing makes sense for many reasons. Of course, one is economics but also the ability to care for aging baby boomers by the younger generations is very important to many who are looking for housing today.

Other priorities include more windows, downstairs bedrooms, home offices, tech/media centers, and flex space. The energy efficiency of a home is of great interest as those in the market for housing want to make sure that they'll be able to reduce their energy bills through the use of greater energy efficient technology.

Increased windows offer more light, which is important to aging baby boomers. If you're selling your home and targeting this market, it's vital to make sure the curtains or shades are open and that you showcase how light and bright your home is, especially in areas like the kitchen, bathroom, and stairwells.

It's easy to understand why downstairs bedrooms are popular among baby boomers. The less climbing of stairs, the better. While the baby boomers might not be using canes or in wheelchairs, having a home that has flexibility for their future needs is of great concern. If your home has a room downstairs and you're using it currently for something other than a bedroom, consider rearranging your home to showcase the downstairs room as a bedroom. It could increase the appeal for baby boomers.

Even though baby boomers are either retired or nearing retirement, many keep working. They often have hobbies and/or jobs that require home offices. Many work well past the age of 65 or, at least, work part-time for a supplemental income. A home office might be a necessity for them.

Tech/media centers are also popular among many other generations than the baby boomers. Having a home that has updated wiring is a big plus. If your home has special features such as wireless home network systems, remote control lighting, and other security features, be sure to highlight them when you're marketing your home for sale. Baby boomers can be very tech savvy so having a home that's smartly wired for advancing technology will win favor with this group and other generations, too.

But perhaps one of the most compelling selling points of a home for baby boomers is flex space. That's the ability to switch the use of one area of the home for something completely different as the baby boomers age. The more flex space a home has, the greater the chances baby boomers can stay in it for a longer period of time. So if you're selling your home and you have one room staged as a den, consider marketing flyers that offer other suggestions for this space such as a bedroom for extended family members.

As with most buyers, regardless of their generation, offering options and showcasing your home's features will help them clearly see the advantages your house has to offer.

Published: December 28, 2012

Use of this article without permission is a violation of federal copyright laws.

Phoebe Chongchua is an award-winning journalist, an author, customer service trainer/speaker, and founder of Setting the Service Standard, a customer service training and consulting program offered by Live Fit Enterprises (LFE) based in San Diego, California. She is the publisher of Live Fit Magazine, an online publication that features information on real estate/finance, physical fitness, travel, and philanthropy. Her company, LFE, specializes in media services including marketing, PR, writing, commercials, corporate videos, customer service training, and keynotes & seminars. Visit her magazine website: www.LiveFitMagazine.com.

Phoebe's articles, feature stories, and columns appear in various publications including The Coast News, Del Mar Village Voice, Rancho Santa Fe Review, and Today's Local News in San Diego, as well as numerous Internet sites. She holds a California real estate license. Phoebe worked for KGTV/10News in San Diego as a Newscaster, Reporter and Community Affairs Specialist for more than a decade. Phoebe's writing is also featured in Donald Trump's book: The Best Real Estate Advice I Ever Received and The Complete Idiot?s Guide to Buying Foreclosures. She is the author of If the Trash Stinks, TAKE IT OUT! 14 Worriless Principles for Your Success.

Contact Phoebe at (858) 259-3646 or . Visit PhoebeChongchua.com for more information.





Source: http://realtytimes.com/rtpages/20121228_babyboomers.htm

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Thursday, December 27, 2012

AEC Q100 Qualified Automotive Pressure Sensor

Designed for 1 Bar (14.7 psi) automotive applications, Melexis MLX90809 pressure sensor meets Automotive Electronics Council (AEC) Q100 requirements.? The piezoresistive microelectromechanical system (MEMS) technology sensor and its signal conditioning circuitry are fabricated in a standard CMOS process producing a completely monolithic sensor on the same wafer.

Signal conditioning includes a low-noise analog front end (AFE), and a 16-bit sigma-delta analog-to-digital converter (ADC) that provide the necessary amplification and offset compensation for the sensing element. The built-in 16-bit microcontroller unit (MCU) circuitry handles temperature compensation and supplies diagnostic mechanisms for safety critical applications.

For more information about Melexis MLX90809 MEMs pressure sensors, click here.

Source: http://www.sensortips.com/pressure/aec-q100-qualified-automotive-pressure-sensor/

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The Stoner Channel: The One with All the Awesome Classic Bluegrass

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Source: http://feeds.gawker.com/~r/gizmodo/full/~3/lfpMh6JbbEo/

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Wednesday, December 19, 2012

Ovarian Cancer - Questions and Answers - Revista Women's Health

What is ovarian cancer?

Ovarian cancer is cancer that starts in the ovaries, the pair of female reproductive organs located in the pelvis. The ovaries have two functions: to produce eggs and female hormones (chemicals that control the way certain cells or organs function). Ovarian cancer occurs when cells in the ovary become abnormal and divide without control or order. Cancer cells can invade and destroy the tissue around them. They can also extend away from the tumor and to form new tumors in other body parts.

Who is at risk?

It is estimated that in the United States, more than 25,000 women will be diagnosed with ovarian cancer in 1999 and more than 14,000 die from the disease. The exact causes of ovarian cancer are unknown. However, studies show that the following factors may increase the likelihood of developing this disease:

Family history. The first-degree relatives (mother, daughter, sister) of a woman who has had ovarian cancer are at increased risk of developing this cancer. The risk is especially high if two or more first-degree relatives of a woman had the disease. A family history of breast cancer or colon is also associated with an increased risk of developing ovarian cancer.

Age. The probability of developing ovarian cancer increases as a woman ages. Most ovarian cancers occur in women over age 50, with more risk for women over 60 years old.

Motherhood. Women who have never had children are more likely to develop ovarian cancer than women who have had them. In fact, the more children they had, the lower the chances of developing ovarian cancer.

Personal History. Women who have had breast cancer or colon, are more likely to develop ovarian cancer than women who have not had these diseases.

Fertility treatment. The fertility treatment with certain drugs that trigger ovulation is associated with a probability higher than average of developing ovarian cancer.

Talc. Some studies suggest that women who have used talc in the genital area for many years may have an increased risk of developing ovarian cancer. However, more research is needed to understand this potential risk factor.

Is there a test to detect ovarian cancer early?

The sooner it is detected and ovarian cancer, the better the chance for recovery. But ovarian cancer is hard to detect early. Many times, women with ovarian cancer have no symptoms or have very mild symptoms until the disease is at an advanced stage. Scientists are studying ways to detect ovarian cancer before symptoms develop.

A large-scale study, known as the study of early detection of cancer of the Prostate, Lung, Colorectal, and Ovarian or PLCO study seeks to determine whether certain evidence will reduce the number of deaths from these cancers. The PLCO trial is currently evaluating the utility of three methods for detecting ovarian cancer.

One is a blood test that measures the level of CA-125, a substance called tumor marker found in the blood often in quantities greater than normal in women with ovarian cancer. This study is also evaluating the effectiveness of a physical examination of the ovaries and a test called a transvaginal ultrasound to detect the disease early.

Transvaginal ultrasound, also known as DVT, is a procedure used to examine the vagina, uterus, fallopian tubes, and bladder. An instrument is inserted into the vagina, and sound waves vibrate the organs inside the pelvic area. These sound waves produce echoes, which uses the computer to create a picture called a sonogram.

Does it cause any symptoms ovarian cancer?

Ovarian cancer usually shows no obvious signs or symptoms until it is advanced development. Signs and symptoms of ovarian cancer may include:

  • General abdominal discomfort or pain (gas, indigestion, pressure, swelling, bloating, cramps).
  • Nausea, diarrhea, constipation, or frequent urination.
  • Loss of appetite.
  • Feeling of fullness even after a light meal.
  • Weight gain or loss without just cause.
  • Abnormal vaginal bleeding.

These symptoms may be caused by ovarian cancer or by other, less serious conditions. It is important to consult your doctor about any of these symptoms.

How is ovarian cancer diagnosed?

To find the cause of symptoms, the doctor evaluates a woman?s medical history, perform a physical examination and order diagnostic tests. Some of the examinations and tests that may be useful are described below:

Pelvic exam. This includes touching the uterus, vagina, ovaries, fallopian tubes, bladder and rectum to find any abnormality in their shape or size. It is usually done along with the pelvic exam Pap test (common test used to detect cervical cancer). Sometimes this test may detect ovarian cancer, but it is not a reliable way to detect or diagnose ovarian cancer.

Ultrasound. It uses high-frequency sound waves. These waves can not be heard by humans, they point to the ovaries. The pattern of the echoes they produce waves creates a picture called a sonogram. Healthy tissues, fluid-filled cysts and tumors look different on the table.

Analysis of CA-125. It consists of a blood test to measure levels of CA-125, a tumor marker in the blood is usually in amounts above normal in women with ovarian cancer.

Lower abdominal radiograph or barium enema. It is a series of x-rays of the colon and rectum. The photographs are taken after the patient is given an enema with a white, chalky solution containing barium. The barium outlines the colon and rectum on the x-ray, making it easier to see the tumor or other abnormal areas.

Computed tomography (CT scan). It is a series of detailed pictures of areas inside the body created by a computer linked to an x-ray machine.

Biopsy. Involves the removal of a tissue sample to be examined under the microscope. A pathologist examines the tissue to make a diagnosis. For tissue, the surgeon performs a laparotomy (incision to open the abdomen).

If cancer is suspected, the surgeon performs an oophorectomy (total excision of the ovary). This is important because, if cancer is present, to cut the outer layer of the ovary to simply remove a tissue sample, maybe cancer cells to escape and spread the disease.

If ovarian cancer is diagnosed, the doctor will want to learn the stage (or extent) of the disease in order to find out whether the cancer has spread and, if so, to what parts of the body. Determining the stage of the disease may involve surgery, x-rays and other methods of making detailed images, and laboratory testing. Knowing the stage of the disease helps the doctor plan treatment.

How is ovarian cancer?

Using different treatments and combinations of treatments to treat ovarian cancer. The plan of treatment for a particular patient depends on several factors, including the stage of the cancer, your age and general health.

Surgery is the treatment for most women diagnosed with ovarian cancer. Generally, ovaries, cervix, uterus, and fallopian tubes are removed by an operation called a hysterectomy with bilateral salpingo-oophorectomy (surgical removal of both fallopian tubes and ovaries).

During surgery determining the stage of the disease and usually involves removing lymph nodes (small organs located along the lymph system ducts) Diaphragm tissue samples, omentum (thin tissue that covers the stomach and intestine) and other organs in the abdomen and abdominal fluid. If the cancer has spread, the surgeon usually removes much of the cancer as possible to reduce the amount of cancer that must then be treated with chemotherapy or radiation therapy.

Chemotherapy is the use of anticancer drugs to kill cancer cells in the body. Most drugs used to treat ovarian cancer are given by injection into a vein (intravenous or IV). There may also be chemotherapy drugs directly into the abdomen (intraperitoneal or IP) via a catheter, a thin tube is placed through the duration of the tratamiento.

Despu?s of chemotherapy is completed, you can make a second look with surgery to examine the abdomen directly. The surgeon may remove fluid and a sample of tissue to see whether anticancer drugs have successfully removed the cancer.

Radiation therapy, also called radiotherapy, involves the use of high energy rays to kill cancer cells. Radiation therapy affects the cancer cells only in the treated area. Radiation may come from a machine (external radiation) or from radioactive liquid placed directly into the abdomen through a catheter (intraperitoneal radiation).

Are clinical trials (research studies) for patients with ovarian cancer?

Yes, clinical trials (research studies) to evaluate new ways to treat cancer are an important treatment option for many women with ovarian cancer. In some studies, all patients receive the new treatment. In others, doctors compare different therapies by giving a group of patients a promising new treatment and other standard therapy group (standard).

Source: http://revistawomenshealth.com/cancer/ovarian-cancer-questions-answers.html

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mankesune: When Going To An Eye Doctor | health and fitness ...

Your eyes are very important for you need the sense of sight to be able to do most of your activities. That is why it is important for one to visit an eye doctor in San Antonio even though he has no problems with his vision. When visiting an ophthalmologist, patients should also prepare themselves.

One thing that you need to do when you want to seek an ophthalmologist in San Antonio is to look for a doctor that will examine you. This can be an easy task if you already have someone that you always go to. However, if this is not the case for you, you should do your homework before going to anyone's clinic.

Even if you will only go to the visit to for a San Antonio eye check up, preparation is still something that is necessary. This is because it can help make the examination or check up easier on your part. Doctors would appreciate it if their patients are prepared for this helps make the session faster and more productive.

Part of the preparation is to get all the necessary things ready before you will go to the clinic. To know what you should bring or do, contact the clinic and ask for the necessary instructions. If you are wearing an eyeglass or contact, you will be asked to bring this. It is also better if you can list your allergies and health history.

If you have health insurance, find out first if this will be accepted in the clinic where you will go to. It would be too inconvenient to go there only to find out that you are not covered. You will also need to bring with you your insurance information for this will be needed by the clinic or any other health facility.

You should take note of the tests the might be done to you. If you know what kind test will be done, you can prepare yourself properly. There are some tests that need some preparation. Doctors will usually tell their patients what to do in advance. If the test is going to impair your vision temporarily, make sure to bring someone with you.

Once you are finished with your visit, you need to be sure that you have taken the necessary things with you especially your prescription. Do not leave is you still have many questions. It is better if you will talk with your doctor while he is still around.

An eye doctor in San Antonio can help you take care of your vision. It is advisable for adults to go to him to have themselves checked. This helps avoid vision problems and deal with issues right away.

Source: http://healthandfitnessupdates.blogspot.com/2012/12/when-going-to-eye-doctor.html

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Source: http://mankesune.blogspot.com/2012/12/when-going-to-eye-doctor-health-and.html

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Tuesday, December 18, 2012

An?lisis del nuevo iMac 2012: dos aciertos, dos errores y una duda razonable

An?lisis del nuevo iMac 2012: dos aciertos, dos errores y una duda razonable

Se ha hecho de rogar pero hace unos d?as el nuevo iMac 2012 se pon?a a la venta en Espa?a. En Xataka ya llevamos unos d?as probando uno de los modelos de 21.5 pulgadas ? que han sido los primeros en estar disponibles ? y tenemos algunas cosas interesantes que contaros sobre nuestra experiencia. ?Ha merecido la pena la reducci?n de grosor? ?Qu? tal se ve la nueva pantalla? ?Y FusionDrive, c?mo se comporta? A estas preguntas le hemos buscado respuestas en nuestro an?lisis del nuevo iMac 2012 en forma de dos aciertos, dos errores y una duda razonable. Acierto 1. Mejorar la calidad de la pantalla Misma resoluci?n, panel IPS pero mucha mejor pantalla. ?Es posible? Pues lo es. El nuevo iMac 2012 acierta de lleno en su apuesta por la calidad de la pantalla y el panel IPS de este nuevo modelo mejora en un aspecto b?sico: reduce hasta en un 75 % los reflejos de los modelos anteriores, que eran ciertamente muy molestos si el entorno lum?nico de trabajo no estaba bajo control. La reducci?n de reflejos es una alegr?a enorme La pantalla del nuevo sobremesa de Apple se ve genial, e incluso con luz natural directa se aprecia una reducci?n brutal de los reflejos (apagada en como mejor se da uno cuenta de esta mejora), con lo que trabajar con ?l es una delicia en ese aspecto. El brillo se mantiene alto sin alcanzar cifras espectaculares, los ?ngulos de visi?n son enormes y tener los p?xeles tan cerca de los ojos del consumidor gracias al nuevo proceso de fabricaci?n de la pantalla permite que la sensaci?n de nitidez y profundidad aumente. Pero ? Error 1. No pantalla Retina por ahora ? Apple ha perdido la oportunidad de ofrecer al menos un modelo premium ? como ha hecho con los Macbook Pro ? en el que la resoluci?n de la pantalla diera un salto de calidad importante. Esa tendencia la estamos viendo en pantallas m?s peque?as, tablets y hasta port?tiles, y los resultados convencen a la mayor?a de los que lo prueban (nuestro an?lisis del MacBook Pro Retina). Esa pasi?n que la compa??a ha puesto en sus pantallas m?s peque?as creo que es un error no haberla traspasado por ejemplo a este modelo de 21.5 pulgadas, ayudando a la hora de trabajar con contenidos y lectura. Sabemos que llegar? en alg?n momento, ?por qu? no ahora? Acierto 2. FusionDrive transparente para el consumidor Aunque el aumento de rendimiento de la gama completa de iMac 2012 es muy notable gracias a los mejores procesadores, m?s RAM y gr?ficas potentes, el acierto m?s importante de Apple ha sido saber ?vender? su sistema FusionDrive. No es ninguna novedad en el mercado el uso de SSD, pero combinar esas memorias flash con discos duros tradicionales de forma transparente para el usuario me parece un acierto pleno, y como os adelantamos cuando os explicamos en qu? consist?a FusionDrive, es una tendencia que llega para quedarse al menos hasta que el precio de GB en unidades SSD no permita optar por este tipo de memorias de forma principal y amplia. El usuario nota una mejor?a sustancial de funcionamiento del equipo, ve solo una unidad y no dos, y es el sistema operativo de Apple el que se encarga de decidir en cada momento en qu? unidad (SSD o disco cl?sico) va cada archivo. Por ahora, la diferencia de rendimiento puede no ser muy apreciable por un usuario dom?stico a primera vista (s? lo notar? en los tiempo de arranque), pero en cuanto te pones a trabajar con grandes archivos o programas que requieren de velocidad a la hora de leer y escribir datos, la opci?n Fusion Drive es muy recomendable. Pero hay que pagarla. La diferencia entre un iMac con Serial ATA de 1 TB a 5400 rpm y un iMac con Fusion Drive de 1 TB es de 250 euros. Adem?s, no en todos los modelos est? disponible (el iMac m?s b?sico de 21.5 pulgadas no permite mejorar esa opci?n), y la capacidad m?xima solo es posible con el iMac de 27 pulgadas(3 TB). En Xataka hemos puesto a prueba una unidad con FusionDrive de 128 GB SSD m?s 1 TB de disco duro (7200 rpm) frente a un modelo de iMac 2012 con la configuraci?n b?sica consistente en un disco duro de 1 TB a 5400 rpm, y en el primer caso hemos obtenido unas velocidades m?ximas de lectura y escritura de 310 y 405 MB/s respectivamente, mientras que en el modelo b?sico sin Fusion Drive, las cifras han arrojado como m?ximo 108 y 105 MB/s. La diferencia es considerable. ?Y si ahora opto por un disco duro cl?sico y m?s adelante, cuando el sistema me lo demande m?s, quiero cambiar a Fusion Drive? Pues muy sencillo, te compras otro iMac. Porque ? Error 2. Cerrar el hardware al l?mite ? Apple ha seguido la idea del mundo del port?til y pese a la filosof?a inicial del ordenador de sobremesa, este iMac es el equipo de Apple ?m?s cerrado de su historia?. Si antes de comprar un equipo inform?tico es conveniente que ajustes presupuesto con necesidades, en el caso del nuevo iMac, tener claro no solo tus necesidades actuales sino futuras es clave. Porque va a ser imposible ampliarlo m?s adelante si no quieres ?despedazarlo?. Si aspiras a m?s RAM, olv?date de comprarla m?s adelante para mejorar el rendimiento. Tendr?s que pasar ahora por la cara caja de Apple para estas ampliaciones. Lo mismo ocurre con el disco duro. Rejilla que sirve de ventilaci?n. Es lo m?s cerca que tendr?s el interior del nuevo iMac Es el sacrificio que un comprador de iMac debe asumir para tener el equipo, aunque nada que no estemos viendo tambi?n en otros sobremesa todo en uno bajo Windows ojo. Apple ha reducido al m?nimo su interior, y compactado todo de tal manera que este iMac se acerca todav?a m?s al universo de los port?tiles, equipos donde uno asum?a de entrada que no iba a ampliar sus posibilidades en el futuro, justo al contrario que con los sobremesa. Pese a todo, hay que alabar de Apple que haya juntado todo un ordenador de sobremesa potente ? ya sin unidad ?ptica ? en un espacio tan reducido. En funcionamiento, el nuevo iMac es tan silencioso que no notas que est? encendido. Y si tem?as por el calor, nada de lo que preocuparse. La carcasa no se calienta en absoluto y la salida de aire posterior es el ?nico punto por el que podemos asumir que se genera calor dentro del equipo. Otro aspecto positivo de este iMac, es el del sonido. Es potente, se escucha bien y no se ha alterado para nada el dise?o frontal ni trasero del equipo para conseguirlo. Pero Apple se deja fuera el tema de los graves, que todav?a siguen sin ser redondos, algo a lo que no ayuda el perfil tan delgado del nuevo iMac. La obsesi?n de Apple por el dise?o de sus productos hace a veces que esa sea la ?nica raz?n por la que obvian poner alg?n puerto USB en el frontal o lateral de su iMac, algo que ser?a c?modo. La duda. ?Es necesario en un sobremesa reducir tanto su grosor? Dicho todo esto, alabada la pantalla, el sonido, la potencia y Fusion Drive, nada m?s abrir el nuevo iMac 2012 para su prueba en Xataka me surgi? una pregunta: ?es necesario en un sobremesa reducir tanto su grosor? ?Tiene alguna misi?n m?s que la apariencia o demostrar de lo que son capaces los ingenieros y dise?adores de Apple? Nuevo iMac 2012 y su famosa ?chepa? Al fin y al cabo, salvo muy contadas excepciones, el iMac no estar? de un lado a otro (el nuevo iMac 2012 de 21.5 pulgadas pesa muy poco) y permanecer? siempre sobre una mesa, donde que la pantalla tenga un grosor como el iMac anterior no repercute en absoluto en el espacio de trabajo de alrededor. ?Era necesario sacrificar una posible ?modulabilidad? ventajosa para el usuario por el dise?o solamente? Otras mejoras que se agradecer?an ser?a una colocaci?n m?s pr?ctica de los puertos, con alguno m?s accesible, as? como una base que permitiera una regulaci?n en altura de la pantalla. Y a nivel de puertos, aunque ha introducido los USB 3.0, todav?a deja de lado algo tan b?sico como el HDMI.

Source: http://www.facebook.com/Xataka/posts/10151179670147636

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6 Ways The Internet Changed Dating | YourTango

How the internet affects dating
Is the internet ruining your dating life?

How has being connected changed your love life?

A startup called FreedomPop recently launched a free 4G wireless service for email and basic web surfing, making 24/7 access to friends and loved ones easier than ever?Just like Google has affected our relationships, the internet has greatly altered our love lives even more so. Let's look at how being connected influences modern dating, for better or for worse.

1. We're Meeting Partners Online
The service that connects us to people we know has also taken on the role of worldwide matchmaker.?Today, one in five couples meet online. And, we're not just finding potential partners on the internet, we're talking to them virtually, dating them, falling in love, and even proposing?online too.?While online dating may not be any better than meeting someone at a bar, many people are still giving digital love a shot. A recent study by MBAPrograms.org found 49 million people search for love each month on eHarmony and Match.com alone. And those are just 2 of the estimated 1,500 online dating sites out there.

More from YourTango: Commitment-Phobic? Blame Mom and Dad

2. We Can Video Chat
Remember when we used to spend hours on the phone? It's almost hard to believe that's how couples communicated before the web. Now, we can see who we're chatting with in realtime on Google Hangouts, Facebook, Skype, FaceTime, you name it. More intimate than a regular phone call, video chats make couples and even strangers feel like they're with each other whether they're at opposite ends of a city or a country.

More from YourTango: Love Bytes: How To Date A Hobbit-Head

3. We Can Talk Any Time
Facebook, Twitter, Tumblr, Skype, Google, Foursquare, LinkedIn, Instagram ? think about all of the online accounts you have (if you can remember). The internet makes us always available. Sure, you can let your email pile up over the week or your Facebook notifications go unnoticed, but doesn't it create some distress or anxiety when you're not tuned in? The second exchange any of our usernames with someone new, we instantly have the ability to connect with them. What's tricky is deciding how much or how little to communicate now that you have access to someone pretty much all the time. Which accounts do you follow and when?

More juicy stories on YourTango:?

Source: http://www.yourtango.com/2012167858/5-ways-internet-changed-dating

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Monday, December 17, 2012

Depardieu reportedly surrendering French passport

PARIS (AP) ? A French newspaper is quoting actor Gerard Depardieu as saying he is turning in his passport after insults from France's Socialist prime minister for taking up residence in tax-friendly Belgium.

The Sunday weekly Le Journal du Dimanche published an open letter attributed to Depardieu in which the actor chides Prime Minister Jean-Marc Ayrault for calling him "pathetic" and "unpatriotic" last week for moving to Belgium to escape French taxes.

"I leave after paying 85 percent of my revenue in 2012," the letter says. "I turn into you my passport and (my) social security card which I have never used."

Depardieu, who turns 64 this month, has made more than 100 films.

The Belgian village of Nechin ? Depardieu's new home ? has drawn other high-earning French residents.

Source: http://news.yahoo.com/depardieu-reportedly-surrendering-french-passport-132257123.html

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Police: 2 survivors in Connecticut school shooting

By NBC News staff

Two adults injured in a shooting at Sandy Hook Elementary School in Connecticut are recovering in the hospital, Connecticut state police confirmed in a news conference Monday.

Initial reports last week suggested only one person had been injured in the attack and survived.

Connecticut state police said those injured will be interviewed once their medical condition improves. Meanwhile, authorities will continue to interview witnesses and painstakingly analyze the evidence found at the school and the shooter's home.

?There are many, many witnesses,? Connecticut State Police Lt. Paul Vance said Monday, adding that any interviews with children will be handled "extremely delicately."

Adam Lanza, who authorities say killed 20 children and six women in Newtown, Conn., shot his mother in the head multiple times before heading to Sandy Hook Elementary School, where he fired hundreds of rounds and died with hundreds more at his disposal, police said.

In addition to?an assault-style rifle and at least two handguns, he also had a shotgun in reserve in the car he drove to the school.

And when he was found, Lanza, 20, still had "hundreds of rounds" of ammunition in multiple magazines, after having already fired hundreds of rounds inside the school, where he killed himself with a gunshot to the head as emergency crews arrived Friday.?

An explanation still hasn't emerged for why Lanza killed the 26 people at Sandy Hook, but Connecticut Gov. Dan Malloy opened a window for speculation when he told NBC News on Sunday that it appeared that Lanza attended the school as a youngster.?Earlier reports that his mother, Nancy, may have taught there haven't borne out.?

"He attended there ? that's what I'm led to believe," Malloy said on NBC's "Meet the Press."


The children ? 12 girls and eight boys, all of them 6 or 7 years old ? were shot as many as 11 times, H. Wayne Carver, the state medical examiner,?said Saturday. It appeared that Lanza had enough weapons and ammunition with him to have killed many, many more.

Police were analyzing the weaponry, along with a computer they found at the Lanzas' home, for possible leads on the gunman's motive, NBC News' Pete Williams reported.

Conn. shooting suspect Adam Lanza's father: 'We too are asking why'

Lanza's parents were divorced, and he lived with his mother, who home-schooled him for part of his childhood, Malloy said.

Connecticut school shooter was 'very nervous around people'

"He had a very troubled life," Malloy said. "He never seemed to be a good fit. ...?It was a very difficult time for him and his mother."

Malloy declined to answer whether any documented evidence had been uncovered that Lanza might have been mentally disturbed. At?Western Connecticut State University in Danbury, where he enrolled at about 16 in 2008, there was never any indication of trouble, the university said in a statement Sunday.

Lanza took six classes ? including website production, data modeling, Philosophy 101 and ethical theory ? and compiled a solid 3.26 grade-point average. ?

Investigators resolutely refused to go into detail about the timing of events Friday during official briefings. But investigators told NBC News that Lanza first killed his mother, an avid gun enthusiast, with her own gun and then took multiple weapons with him as he drove to the school in her car.

To bypass security, Lanza smashed in a window, they said. He shot and killed Principal Dawn Hochsprung, 47, and Mary Sherlach, 56, a school psychologist, before proceeding to a classroom, where he found the door locked.

So he moved on to a second classroom, where he killed everyone he found, before doing the same in a third classroom, investigators believe. He then shot himself.

Watch US News crime videos on NBCNews.com

Although he was carrying three weapons, he used only one of them in all of the school killings ? a Bushmaster .223-caliber assault-style rifle similar to the one used by the snipers who terrorized the Washington, D.C., area in 2002. It was purchased legally, they said. He used one of the handguns to kill himself.

Authorities haven't said how Nancy Lanza stored the weapons.?

Marsha Lanza, Nancy Lanza's sister-in-law and Adam Lanza's aunt, said there was a good reason for a divorced woman who grew up with guns to have them in the house: self-defense.

"She lived alone. She was a female (who) lived alone," Marsha Lanza said.

Chief Justice Correspondent Pete Williams and Isolde Raftery of NBC News?contributed to this report.

Source: http://usnews.nbcnews.com/_news/2012/12/17/15969867-police-2-survivors-in-connecticut-school-shooting?lite

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Sunday, December 16, 2012

Don't Think that Health, Beauty and Fitness are only a ...

?

Franchises are all the rage, and if the statisticians are correct,?opening a franchise and becoming a franchisee will be the most sought
after career in 2013. BAM Brands is one?company that is mentioned frequently when speaking about the franchise?world. Why is that? Because this is the one and only company that has?its finger on the pulse of the health and beauty industry at all
times.

So?why is the health and beauty industry so popular? Oh, come on?now?as you get all geared up to attend the numerous Christmas parties?in your near future you should know the answer to that question.?Health, beauty and fitness doesn?t even fall into the popular category?- they fall into the category of outright obsession. When you look at?your dressing table, or at your sink filled with cosmetics, hair care?products and more ? you know immediately that health and beauty is a?large part of everyday life. And because of the amazing franchises:MassagLuXe, Spray La Vie; The TAN Company and Xist Fitness -?BAM Brands has made their mark on the world
of health, beauty and fitness. A mark so large that they will go into?the record books and join the long history of the health and beauty
industry that took over human lives.

If you want to really go back and explore ? as sort of a Christmas??fun? journey ? it was the queen of beauty, once called Cleopatra, who
came to the decision that baths of milk and honey were the only way to?go in order to make her skin the best it could possibly be. (The asps
liked it, too.)

And it seems that every female since (and the males, too, by the way.?Don?t think that health, beauty and fitness are only a woman?s?domain), has been drawn to everything from cosmetics to spray tans to?the ultimate massage that removes the tension and stress of everyday?life.

Beauty and relaxation are what you would call the ultimate pleasures.?And when it comes to physical fitness ? the world of Xist Fitness?by BAM Brands - is a true ?gift? at
Christmastime (and any other time) for people who want nothing more?than to be healthy and stay in shape. Let?s say that Cleopatra would?have LOVED a gift card from any of the BAM Brand
companies.

Over the centuries, women have taken care of everything from lips,?eyes and ears to stomachs and skin ? now wanting that spray tan more?than ever before supplied by The TAN Company and Spray LaVie. Humans have infused their lives with the basics when it?comes to beauty and fitness. And, thankfully, they no longer have to?suffer as they once did for silky skin and perfection.

When you speak about torture and suffering for beauty, the first thing?that comes to mind is the Renaissance era when the wealthy class of European women plucked?their natural hairline all the way back to the crown of their head.?No, not kidding. This was actually something they wanted to do in
order to give themselves high rounded foreheads. (Thankfully, we?re?down to plucking only eyebrows now, and considering how much that?hurts?you can only imagine how it would feel to take off the?hairline.)

Her skin is like porcelain. You know that phrase? Well, it actually was once. At one time women had to whiten their skin using a lethal combination of vinegar and lead. Queen Elizabeth is the one remembered most for this process, and she was the one who ordered all mirrors banned from the castle. (I wonder why?)

?

Ancient Egyptians used their own type of poison in order to make their?eyes glitter, a potion that eventually caused them to go blind.
Whereas some women used nightshade to dilate their pupils in order to?make them look interested. What they did was receive glaucoma for?their efforts.

And you don?t even want to know what people went through in the?fitness category. From tight garments to causing themselves to become?anemic ? many passed away early just for the sake of fitness. And?although piercing and tattoos have remained in the culture, the?medicine and cleanliness behind these particular ?beauty? devices have?come a long way since these things first began.

So how does BAM Brands fit into the history?of all this pain, torture and anguish? By being the easy, painless,?innovative and kind companies that offer health and fitness, beauty?regimes, massage, and tanning that helps the skin be both amazing to?look at and extremely healthy. Yup! Thank goodness for the?21st Century?it?s a whole heck of a lot nicer with?BAM Brands in our world.

So when you head out to those Christmas and New Year?s parties, just?remember that it?s because of companies that BAM
Brands
created that you look good, feel relaxed and can?really enjoy the holiday season!

?

For more information, head to:

www.bamfran.com

-->

Source: http://chandlerlocalnews.com/?p=50

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Source: http://ukutereliri.posterous.com/don39t-think-that-health-beauty-and-fitness-a

juan williams

Morgan Freeman Blames "Sensationalist Media" for Connecticut Shooting [Updated]

Source: http://www.thehollywoodgossip.com/2012/12/morgan-freeman-blames-sensationalist-media-for-connecticut-shoot/

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Steel firm settles religious accommodation suit ? Business ...

Pittsburgh-based steel-industry supplier Magnetics International will pay $30,000 to settle a religious discrimination suit filed by an employee in Indiana who claimed the company failed to accommodate his need to worship regularly.

At the time Daniel began working as a laborer at the company, he explained that his Christian beliefs required him to attend church at least every other Sunday. Magnetics agreed to the arrangement, but Daniel?s religion became a polarizing issue.

When the company scheduled him to work on two consecutive Sundays, he reminded his employer of the conflict it would cause. According to Daniel?s complaint, Magnetics insisted he had to work as scheduled and offered no other possible accommodations. Daniel refused to work the second Sunday, and he was fired.

He filed a complaint with the EEOC, which tried to mediate the dispute. When those efforts were unsuccessful, it sued on Daniel?s behalf. Only then did Magnetics offer to settle.

Under the settlement, Magnetics must pay Daniel $30,000 and respond appropriately to all requests for religious accommodation for the next three years. The terms of the settlement also require the company to post a nondiscrimination policy, provide employee training and regularly report its compliance efforts to the EEOC.

Advice: Once you make an accommodations deal with an employee, stick with it. Changing the terms later can easily provoke a lawsuit.

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John Kerry To Get Secretary Of State Nomination, Reports ABC

  • Hillary Clinton (2009-present)

    U.S. Secretary of State Hillary Clinton speaks at a press conference on November 14, 2012. (Source: <a href="http://www.state.gov/secretary/former/">U.S. Department Of State</a>)

  • Condoleezza Rice (2005-09)

    Secretary of State Condoleezza Rice talks about the State Department's 2007 Country Reports on Human Rights Practices during a March 11, 2008 briefing in Washington. (Source: <a href="http://www.state.gov/secretary/former/">U.S. Department Of State</a>)

  • Colin Powell (2001-05)

    U.S. Secretary of State Colin Powell speaks on June 22, 2004, about a corrected version of an inaccurate terrorism report issued by the government. (Source: <a href="http://www.state.gov/secretary/former/">U.S. Department Of State</a>)

  • Madeleine Albright (1997-2001)

    U.S. Secretary of State Madeleine Albright delivers a Russia policy briefing on September 16, 1999 in Washington. (Source: <a href="http://www.state.gov/secretary/former/">U.S. Department Of State</a>)

  • Warren Christopher (1993-97)

    U.S. Secretary of State Warren Christopher briefs reporters on the peace process in Bosnia during a Dec. 8, 1995 press conference. (Source: <a href="http://www.state.gov/secretary/former/">U.S. Department Of State</a>)

  • Lawrence Eagleburger (1992-93)

    Then-acting Secretary of State Lawrence Eagleburger listens to a reporter's question during a Nov. 18, 1992 news conference at the State Department. (Source: <a href="http://www.state.gov/secretary/former/">U.S. Department Of State</a>)

  • James Baker (1989-92)

    James Baker III waves to his associates at the US State Department on August 13, 1992. (Source: <a href="http://www.state.gov/secretary/former/">U.S. Department Of State</a>)

  • George P. Shultz (1982-89)

    U.S. Secretary of State George Shultz listens to a question during his first day of testimony before Iran-Contra investigators on July 23, 1987 in Washington. (Source: <a href="http://www.state.gov/secretary/former/">U.S. Department Of State</a>)

  • Alexander Haig (1981-82)

    Alexander Haig, Secretary of State-designate, a Reagan nominee on Monday, Dec. 23, 1980 in Washington for the announcement of selections. (Source: <a href="http://www.state.gov/secretary/former/">U.S. Department Of State</a>)

  • Edmund Muskie (1980-81)

    (Pictured left) Freed hostage Richard Queen, right, greets well wishers at the State Department on Monday, July 21, 1980 in Washington. At left is Secretary of State Edmund Muskie. (Source: <a href="http://www.state.gov/secretary/former/">U.S. Department Of State</a>)

  • Cyrus Vance (1977-80)

    Cyrus Vance, U.S. Secretary of State, pictured in 1979. (Source: <a href="http://www.state.gov/secretary/former/">U.S. Department Of State</a>)

  • Henry Kissinger (1973-77)

    Secretary of State Henry Kissinger announces during an April 29, 1975 press conference in Washington that the evacuation of Americans from Vietnam and Saigon is complete, thus ending US involvement. (Source: <a href="http://www.state.gov/secretary/former/">U.S. Department Of State</a>)

  • William P. Rogers (1969-73)

    Israeli Defense Minister Moshe Dayan, left, and Secretary of State William P. Rogers begin talks at the Department of State on Feb. 7, 1972 in Washington. (Source: <a href="http://www.state.gov/secretary/former/">U.S. Department Of State</a>)

  • Dean Rusk (1961-69)

    Secretary of State Dean Rusk is shown during a news conference in Washington, D.C., on March 1, 1962. (Source: <a href="http://www.state.gov/secretary/former/">U.S. Department Of State</a>)

  • Christian Herter (1959-61)

    President Dwight Eisenhower, left, says goodbye to Secretary of State Christian Herter in Gettsburg, Pennsylvania, on May 2, 1959 as Herter is about to board a helicopter on the President's farm to return to Washington. (Source: <a href="http://www.state.gov/secretary/former/">U.S. Department Of State</a>)

  • John Foster Dulles (1953-59)

    U.S. Secretary of State John Foster Dulles (left) gets together with South Korean President Syngman Rhee in Seoul on August 4, 1953. (Source: <a href="http://www.state.gov/secretary/former/">U.S. Department Of State</a>)

  • Dean Acheson (1949-53)

    U.S. Secretary of State Dean Acheson speaks from the State Department on Nov. 29, 1950 in Washington. (Source: <a href="http://www.state.gov/secretary/former/">U.S. Department Of State</a>)

  • George C. Marshall (1947-49)

    Gen. George C. Marshall poses in his Red Cross office on Sept. 13, 1950 in Washington. (Source: <a href="http://www.state.gov/secretary/former/">U.S. Department Of State</a>)

  • James F. Byrnes (1945-47)

    James F. Byrnes, United States Secretary of State, links arms with Associated Press correspondent, John Hightower, at Central Hall, Westminster in London, Jan. 15, 1946. (Source: <a href="http://www.state.gov/secretary/former/">U.S. Department Of State</a>)

  • Edward Reilly Stettinus (1944-45)

    France's Foreign Minister Georges Bidault makes a VE Day radio statement from the Opera House in San Francisco, CA, May 8, 1945. Seated at the far right U.S. Secretary of State Edward Stettinius. (Source: <a href="http://www.state.gov/secretary/former/">U.S. Department Of State</a>)

  • Cordell Hull (1933-44)

    U.S. President Franklin Roosevelt is greeted by Secretary of State Cordell Hull on Sept. 15, 1938 in Washington. (Source: <a href="http://www.state.gov/secretary/former/">U.S. Department Of State</a>)

  • Henry Lewis Stimson (1929-33)

    Henry Lewis Stimson, American Secretary of State for War shown around July 1931. (Source: <a href="http://www.state.gov/secretary/former/">U.S. Department Of State</a>)

  • Frank B. Kellogg (1925-29)

    Former United States Secretary of State Frank B. Kellogg on Aug. 17, 1936 at Waterloo Station in London. (Source: <a href="http://www.state.gov/secretary/former/">U.S. Department Of State</a>)

  • Charles Evans Hughes (1921-25)

    (Center) Former Secretary of State and Chief justice Charles Evans Hughes, pictured on on March 27, 1931. (Source: <a href="http://www.state.gov/secretary/former/">U.S. Department Of State</a>)

  • Source: http://www.huffingtonpost.com/2012/12/15/john-kerry-secretary-of-state_n_2306877.html

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    Saturday, December 15, 2012

    Julie Spira: Holiday Dating: Should You Rekindle the Spark With an ...

    Being single at the holidays is emotional for most, but it also gives you the chance to reflect on relationships of your past.

    If you're thinking of reconnecting with a former love at the holidays, you're not alone.

    As a dating expert and relationship coach, many of my clients and their friends are telling me they've reconnected this holiday season with long-lost loves. Yes, you're recycling an ex, but why not give it a shot again with someone you have a history with and still have fond memories of?

    Perhaps it starts off innocently in November with a text message or email saying "Happy Thanksgiving." It's a safe way to reach out and reconnect without feeling you'll get rejected by picking up the phone.

    Often, you may receive a favorable reply, which makes you feel warm and fuzzy.

    The next thing you know, you're projecting into the future wondering if you should ask him or her to the office holiday party. What are their Christmas and New Year's plans? Could you be kissing under the mistletoe?

    With holiday break-up season at its peak, it's normal to wonder if he or she is in a relationship or still thinks about you from time-to-time.

    What are the rules and proper etiquette for recycling an ex at the holidays?

    Here are five tips on how to reconnect or attend a special holiday event with your former beau or girlfriend, to make it a better experience for all involved.

    1. Don't talk about what went wrong. You know the reason you broke up. He or she knows the reason you broke up. There's no need to rehash the past and spend time going down memory lane.

    2. Don't talk about your dating history while you were apart. Perhaps one of you had a lusty affair and the other never got over your initial break-up. There's no reason to compare bad date stories or wonder how many people your ex went to bed with. Keep the conversation on a need-to-know basis. They simply don't need to know what happened during your hiatus.

    3. Do keep the conversation light and easy. Just like your initial first dates, remember to leave the drama behind. You might think the familiarity should allow you to accelerate things, but being a "Debbie or Donnie Downer" will turn him or her away faster than you can imagine. Ask about his or her family and how work is going, or talk about the latest accomplishments of your children. If your former love interest says they're seeing someone, respect their relationship status and don't try to talk them out of it.

    4. Don't try to pick up where you left off. Don't assume your ex wants to get back together long-term. Try and look at this as a new friendship or the beginning of a new relationship that just happened to resurface during the holidays. Don't start planning your future all over again and keep the expectations low. Live in the moment on your first date together.

    5. Don't sleep together. Avoid being overly affectionate in public the first time you see each other after a break-up. Unless you really want a friends-with-benefits relationship, don't immediately end up back in bed. You may wake up regretting it in the morning, when your emotions are at an all-time high, as your mind wanders off thinking where the relationship is headed.

    If things go well when you reunite over the holidays and you decide to start dating your ex, keep the communication going. Sending only a text message to say that you had a great time instead of calling the next day won't win her heart. If you're truly interested in pursuing the relationship again, pick up the phone and call to set up another date.

    If you have personally experienced recycling an ex, feel free to share your stories and comment.


    Julie Spira is an online dating and relationship expert. She creates irresistible profiles for singles on the dating scene. Julie's the author of the bestseller, The Perils of Cyber-Dating. For more dating advice, visit CyberDatingExpert.com, where you can sign up for the Weekly Flirt. Follow @JulieSpira on Twitter and at Facebook.com/CyberDatingExpert.

    ?

    ?

    ?

    Follow Julie Spira on Twitter: www.twitter.com/JulieSpira

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    Source: http://www.huffingtonpost.com/julie-spira/holiday-dating-ex-relationships_b_2286449.html

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    New findings on killer bacteria's defence

    New findings on killer bacteria's defence [ Back to EurekAlert! ] Public release date: 14-Dec-2012
    [ | E-mail | Share Share ]

    Contact: Pontus Nordenfelt
    pontus.nordenfelt@childrens.harvard.edu
    857-225-3050
    Lund University

    Antibodies are key to the recognition and neutralisation of bacteria by our immune system. The most common antibodies have the shape of a Y, and the two prongs fasten to molecules that belong to the bacteria. The cells in the immune system recognise the shaft and can then attack the bacteria.

    Since the 1960s, it has been known that certain bacteria have developed the ability to turn these antibodies around, which makes it more difficult for the immune system to identify them. These include streptococcus bacteria, sometimes referred to as 'killer bacteria', that cause both common tonsillitis and more serious diseases such as sepsis (blood poisoning) and necrotising fasciitis (flesh-eating disease). Because it has not been possible to study this phenomenon in detail, researchers have until now presumed that antibodies are always turned around in these streptococcal infections.

    Now researchers at Lund University have shown that this is not the case. In less serious conditions, such as tonsillitis, the antibodies are back-to-front, but in more serious and life-threatening diseases such as sepsis and necrotising fasciitis, the antibodies are the right way round. These findings have now been published in the Journal of Experimental Medicine and completely alter the understanding of bacterial infections with several of our most common pathogenic bacteria.

    "This information is important and fundamental to improving our understanding of streptococcal infections, but our results also show that the principle described could apply to many different types of bacteria", says Pontus Nordenfelt, who is currently conducting research at Harvard Medical School in Boston.

    The present study shows that it is the concentration of antibodies in the local environment in the body that controls how the antibodies sit on the surface of the bacteria. In the throat, for example, where the concentration is low, the antibodies sit the wrong way round, but in the blood, where the concentration is high, the antibodies are the right way round. This explains why the most serious infections are so rare in comparison to the common and often mild cases of throat and skin infections.

    The bacteria in the blood are quite simply easier for the immune system to find.

    In the future, the results could have an impact on the treatment of serious infectious diseases, since a better understanding of the mechanisms behind the diseases is needed to develop new treatments.

    Lars Bjrck, Professor of Infectious Medicine at Lund University, has discovered some of the antibody-turning proteins and has studied their structure and function for over 30 years.

    "It is fantastic to have been involved in moving a major step closer to understanding the biological and medical importance of these proteins together with talented young colleagues", he says.

    ###

    For more information:

    Pontus Nordenfelt, pontus.nordenfelt@childrens.harvard.edu, telephone: +1 857 225 3050

    Link to article in the Journal of Experimental Medicine

    'Antibody orientation at bacterial surfaces is related to invasive infection'. Pontus Nordenfelt, Sofia Waldemarson, Adam Linder, Matthias Mrgelin, Christofer Karlsson, Johan Malmstrm and Lars Bjrck. The Journal of Experimental Medicine.


    [ Back to EurekAlert! ] [ | E-mail | Share Share ]

    ?


    AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


    New findings on killer bacteria's defence [ Back to EurekAlert! ] Public release date: 14-Dec-2012
    [ | E-mail | Share Share ]

    Contact: Pontus Nordenfelt
    pontus.nordenfelt@childrens.harvard.edu
    857-225-3050
    Lund University

    Antibodies are key to the recognition and neutralisation of bacteria by our immune system. The most common antibodies have the shape of a Y, and the two prongs fasten to molecules that belong to the bacteria. The cells in the immune system recognise the shaft and can then attack the bacteria.

    Since the 1960s, it has been known that certain bacteria have developed the ability to turn these antibodies around, which makes it more difficult for the immune system to identify them. These include streptococcus bacteria, sometimes referred to as 'killer bacteria', that cause both common tonsillitis and more serious diseases such as sepsis (blood poisoning) and necrotising fasciitis (flesh-eating disease). Because it has not been possible to study this phenomenon in detail, researchers have until now presumed that antibodies are always turned around in these streptococcal infections.

    Now researchers at Lund University have shown that this is not the case. In less serious conditions, such as tonsillitis, the antibodies are back-to-front, but in more serious and life-threatening diseases such as sepsis and necrotising fasciitis, the antibodies are the right way round. These findings have now been published in the Journal of Experimental Medicine and completely alter the understanding of bacterial infections with several of our most common pathogenic bacteria.

    "This information is important and fundamental to improving our understanding of streptococcal infections, but our results also show that the principle described could apply to many different types of bacteria", says Pontus Nordenfelt, who is currently conducting research at Harvard Medical School in Boston.

    The present study shows that it is the concentration of antibodies in the local environment in the body that controls how the antibodies sit on the surface of the bacteria. In the throat, for example, where the concentration is low, the antibodies sit the wrong way round, but in the blood, where the concentration is high, the antibodies are the right way round. This explains why the most serious infections are so rare in comparison to the common and often mild cases of throat and skin infections.

    The bacteria in the blood are quite simply easier for the immune system to find.

    In the future, the results could have an impact on the treatment of serious infectious diseases, since a better understanding of the mechanisms behind the diseases is needed to develop new treatments.

    Lars Bjrck, Professor of Infectious Medicine at Lund University, has discovered some of the antibody-turning proteins and has studied their structure and function for over 30 years.

    "It is fantastic to have been involved in moving a major step closer to understanding the biological and medical importance of these proteins together with talented young colleagues", he says.

    ###

    For more information:

    Pontus Nordenfelt, pontus.nordenfelt@childrens.harvard.edu, telephone: +1 857 225 3050

    Link to article in the Journal of Experimental Medicine

    'Antibody orientation at bacterial surfaces is related to invasive infection'. Pontus Nordenfelt, Sofia Waldemarson, Adam Linder, Matthias Mrgelin, Christofer Karlsson, Johan Malmstrm and Lars Bjrck. The Journal of Experimental Medicine.


    [ Back to EurekAlert! ] [ | E-mail | Share Share ]

    ?


    AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


    Source: http://www.eurekalert.org/pub_releases/2012-12/lu-nfo121412.php

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    Wednesday, December 12, 2012

    Boehner: 'Serious differences' remain in talks

    House Speaker John Boehner of Ohio, who conferred with President Barack Obama by phone yesterday, speaks during a news conference on Capitol Hill in Washington, Wednesday, Dec. 12, 2012, following a closed-door meeting with the GOP caucu. Boehner and the other House Republican leaders are calling for Obama to come up with plan they can accept for spending cuts and tax revenue to avoid the so-called "fiscal cliff" of automatic tax hikes and budget reductions. (AP Photo/J. Scott Applewhite)

    House Speaker John Boehner of Ohio, who conferred with President Barack Obama by phone yesterday, speaks during a news conference on Capitol Hill in Washington, Wednesday, Dec. 12, 2012, following a closed-door meeting with the GOP caucu. Boehner and the other House Republican leaders are calling for Obama to come up with plan they can accept for spending cuts and tax revenue to avoid the so-called "fiscal cliff" of automatic tax hikes and budget reductions. (AP Photo/J. Scott Applewhite)

    House Speaker John Boehner of Ohio, who spoke with President Barack Obama yesterday, arrives for a closed-door meeting with the GOP caucus, Wednesday, Dec. 12, 2012, on Capitol Hill in Washington. Boehner and the other House Republican leaders are calling for Obama to come up with plan they can accept for spending cuts and tax revenue to avoid the so-called "fiscal cliff" of automatic tax hikes and budget reductions. (AP Photo/J. Scott Applewhite)

    FILE - This Nov. 16, 2012 file photo shows President Barack Obama, accompanied by House Speaker John Boehner of Ohio, speaking to reporters in the Roosevelt Room of the White House in Washington. Even if Congress and the White House fail to strike a budget deal by New Year's Day, reality may be a lot less bleak then the scenario that's been spooking employers and investors and slowing the U.S. Economy. The tax increases and spending cuts could be retroactively repealed after Jan. (AP Photo/Carolyn Kaster, File)

    House Majority Leader Eric Cantor of Va., right, accompanied by Rep. Cathy McMorris Rodgers, R-Wash, gestures as he speaks to reporters during a news conference on Capitol Hill in Washington, Wednesday, Dec. 12, 2012, following a GOP strategy session. (AP Photo/J. Scott Applewhite)

    (AP) ? House Speaker John Boehner said Wednesday that "serious differences" remain between him and President Barack Obama in negotiations on averting automatic spending cuts and tax increases that economists say could send the U.S. economy over a "fiscal cliff."

    Boehner's comments came as top Democrats pushed back on GOP demands for tough steps such as raising the Medicare eligibility age and curbing the cost-of-living adjustment for Social Security.

    Boehner and Obama spoke on the phone Tuesday, a day after the president offered to reduce his initial demand for $1.6 trillion in higher tax revenue over a decade to $1.4 trillion. But Obama continues to insist that much of the revenue come from raising top tax rates on the wealthy.

    Boehner countered later Tuesday with another offer that GOP aides said stuck close to a document delivered to the White House a week ago. A top White House aide, Rob Nabors, came to the Capitol to respond. A Democratic official said Boehner's counter-offer included permanent extension of Bush-era tax rates for all taxpayers including the top 2 percent of earners, the same as his earlier proposal. Boehner offers $800 billion in new revenues through a tax reform measure next year. The officials spoke only on condition of anonymity because they were not authorized to describe the private talks.

    Boehner on Wednesday offered a sour assessment less than three weeks before the cliff deadline. The changes would strike the economy with $500 billion worth of spending cuts and higher tax rates if left in place through September.

    "There were some offers that were exchanged back and forth yesterday and the president and I had pretty frank conversations about just how far apart we are," the Ohio Republican said after a closed-door meeting with fellow GOP lawmakers in which he advised them not to make plans for the week after Christmas.

    Leading lawmakers expressed pessimism that a deal was close, despite increasing angst about a Dec. 31 deadline to stop the expiration of Bush-era tax cuts and separate across-the-board spending cuts that are the result of Washington's failure to complete a deficit-reduction deal last year.

    "I think it's getting worse, not better," House GOP Whip Kevin McCarthy, R-Calif., said.

    Obama met Wednesday with nine mayors from around the country and spoke to more on a conference call about the fiscal cliff. Following the meeting, the mayors said it was important for Congress to come to agreement with the White House on a "balanced approach."

    Columbus, Ohio, Mayor Michael Coleman said he did not "detect frustration" in Obama during the meeting. "But I can tell you that we're frustrated, and I think America is becoming frustrated. I think those in Ohio are becoming frustrated and those in Columbus are becoming frustrated because it seems this can be done, that we can forge an agreement with Congress that will result in tax cuts for the middle class."

    The Boehner camp again said it's up to the White House to proffer additional spending cuts to programs like Medicare. The White House countered that Republicans still need to cave on raising tax rates for the rich.

    House Minority Leader Nancy Pelosi, meanwhile, warned Republicans against insisting on raising the Medicare eligibility age as part of any deal.

    "One of the things that we object to is raising the Medicare age," Pelosi said on "CBS This Morning." ''Don't go there."

    Pelosi said raising the retirement age wouldn't contribute much savings toward an agreement, adding "Is it just a trophy that the Republicans want to take home?"

    Raising the Medicare age from 65 to 67 could cut Medicare costs by $162 billion over a decade, according to a Congressional Budget Office estimate last year. But by 2035, it would cut Medicare's projected budget by 7 percent.

    Democrats also pushed back against a GOP plan to reduce Social Security COLAs. That's a step back from talks between Obama and Boehner 18 month ago in which Obama considered the lower COLA.

    "Quite frankly, Social Security is off the table," said Rep. Joe Crowley, D-N.Y.

    But in an ABC interview Tuesday, Obama did not reject a Republican call to raise the age of Medicare eligibility from 65 to 67, a proposal many Democrats strongly oppose.

    The proposal is "something that's been floated," Obama said, not mentioning that he had tacitly agreed to it in deficit-reduction talks with Boehner more than a year ago that ended in failure.

    "When you look at the evidence, it's not clear that it actually saves a lot of money," Obama said. "But what I've said is, let's look at every avenue, because what is true is we need to strengthen Social Security, we need to strengthen Medicare for future generations, the current path is not sustainable because we've got an aging population and health care costs are shooting up so quickly."

    The White House, for its part, detailed numerous proposals Obama has made to cut spending, including recommendations to cull $340 billion from Medicare over a decade and an additional $250 billion from other government benefit programs.

    Obama remains determined that tax rates rise on family income exceeding $250,000, a move Republicans say would strike many small businesses that are engines of new jobs and file as individuals when paying their taxes.

    Two weeks before the year-end holidays, time to find agreement was short, but not prohibitively so.

    "I think it's going to be extremely difficult to get it done before Christmas, but it could be done," Senate Majority Leader Harry Reid, D-Nev., said.

    Democrats have watched with satisfaction in recent days as Republicans struggle with Obama's demands to raise taxes, but Reid privately has told his rank and file they could soon be feeling the same distress if discussions grow serious on cuts to benefit programs.

    Obama's plan would raise $1.6 trillion in revenue in part by raising tax rates on incomes over $200,000 for individuals and $250,000 for couples. He has recommended $400 billion in spending cuts over a decade.

    He also is seeking extension of the Social Security payroll tax cut due to expire Jan. 1, a continuation in long-term unemployment benefits and steps to help hard-pressed homeowners and doctors who treat Medicare patients.

    The White House summary noted that Obama last year signed legislation to cut more than $1 trillion from government programs over a decade, and was proposing $600 billion in additional savings from benefit programs.

    Boehner's plan, in addition to calling for $800 billion in new revenue, envisions $600 billion in savings over a decade from Medicare, Medicaid and other government health programs, as well as $300 billion from other benefit programs and another $300 billion from other domestic programs.

    Associated Press

    Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2012-12-12-Fiscal%20Cliff/id-ac4fba75db4a497b90b565721ef94925

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    Society of Genealogists Family History Skills Courses ? starts

    Wednesday, December 12th, 2012 at 2:58 pm ?

    The Society?s successful family history skills evening courses begins again with the first ten-week series of classes for those who are new to family history or who have had a little experience and want to build upon their initial progress. Our team of professional genealogists will introduce the records and illustrate how they should best be used for the study of family history. Publications, electronic finding aids and the internet will, of course, be included along with all the basic sources needed to start research. Stage 1 will run from 24 Jan -11 April, cost ?150.00/?120.00 SoG members.

    The Stage 2? series is designed for those who already have some experience of genealogical research and are familiar with the basic records (General Registration, the censuses, directories, parish registers and bishops? transcripts and wills). The course will introduce students to many of the records and finding aids used to take research further. In addition to a description of the records and their whereabouts, sources will be put into the context of their original purpose and the techniques required in their use in genealogical research. Stage 2 will take place 23 May ? 25 July, cost ?150.00/?120.00 SoG members

    Stage 3 ? This final series of courses will stretch students of all abilities and, above all, will be an entertaining and enjoyable experience along with helping you to become a knowledgeable family historian. Classes will include a practical element with assignments and is suitable for students wishing to take the IHGS examinations. Stage 3 will take place 5 Sept ? 7 Nov, cost??150.00/?120.00 SoG members.

    Thursday evenings from 6-8pm, with tutors Else Churchill, Geoff Swinfield, Paul Blake and Ian Waller. Each stage can be booked individually, but book all three together and receive a 10% discount. For a full programme, please contact the events department, by email or by telephone: 020 7553 3290.

    To?make a booking online, SoG members should first log into the MySoG? area of the website in order to enter the online shop and make bookings.? Non-members are also welcome to attend events, and the programme can be viewed by visiting our online shop.

    ? 2012, Society of Genealogists. All rights reserved.

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    Source: http://www.societyofgenealogists.com/society-of-genealogists-family-history-skills-courses-starts-thursday-evenings-on-24-january/

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